ID A4IHE6_XENTR Unreviewed; 186 AA.
AC A4IHE6; F7DA28;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Biliverdin reductase B {ECO:0000313|Ensembl:ENSXETP00000058377};
DE SubName: Full=Flavin reductase (NADPH) {ECO:0000313|RefSeq:NP_001096269.1};
DE SubName: Full=LOC100124834 protein {ECO:0000313|EMBL:AAI35496.1};
GN Name=blvrb {ECO:0000313|Ensembl:ENSXETP00000058377,
GN ECO:0000313|RefSeq:NP_001096269.1,
GN ECO:0000313|Xenbase:XB-GENE-1006837};
GN Synonyms=LOC100124834 {ECO:0000313|EMBL:AAI35496.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI35496.1};
RN [1] {ECO:0000313|RefSeq:NP_001096269.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI35496.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole embryo {ECO:0000313|EMBL:AAI35496.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000058377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000058377};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000058377}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2020) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001096269.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC135495; AAI35496.1; -; mRNA.
DR RefSeq; NP_001096269.1; NM_001102799.1.
DR DNASU; 100124834; -.
DR Ensembl; ENSXETT00000062907; ENSXETP00000058377; ENSXETG00000016957.
DR GeneID; 100124834; -.
DR KEGG; xtr:100124834; -.
DR AGR; Xenbase:XB-GENE-1006837; -.
DR CTD; 645; -.
DR Xenbase; XB-GENE-1006837; blvrb.
DR OrthoDB; 2511224at2759; -.
DR Proteomes; UP000008143; Chromosome 8.
DR Bgee; ENSXETG00000016957; Expressed in liver and 12 other cell types or tissues.
DR CDD; cd05244; BVR-B_like_SDR_a; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43355; FLAVIN REDUCTASE (NADPH); 1.
DR PANTHER; PTHR43355:SF2; ZGC:91854; 1.
DR Pfam; PF13460; NAD_binding_10; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 6..169
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF13460"
SQ SEQUENCE 186 AA; 20354 MW; 2B7D0023D95659E2 CRC64;
MSRFSGYNVN VLVRDPARLP SGQNPTTVTV GDVLNKNDVL KTLKGQEAVV IVLGTRNDLG
PTTMMSEGTQ NIVEAMKLLG IRKVVACMSS FLLWDIAKVP PTLLPVTEDH IRMHQVLKDS
GLDYVAVLPP HIAADKPFTG EYTVTVGTRG GNVISTHDLS HFFLQCLTTN EYNGKNVTLS
RDYSNL
//
