GenomeNet

Database: UniProt
Entry: A4IK95
LinkDB: A4IK95
Original site: A4IK95 
ID   LUTB_GEOTN              Reviewed;         476 AA.
AC   A4IK95;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   16-JAN-2019, entry version 76.
DE   RecName: Full=Lactate utilization protein B {ECO:0000255|HAMAP-Rule:MF_02103};
GN   Name=lutB {ECO:0000255|HAMAP-Rule:MF_02103};
GN   OrderedLocusNames=GTNG_0367;
OS   Geobacillus thermodenitrificans (strain NG80-2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=420246;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NG80-2;
RX   PubMed=17372208; DOI=10.1073/pnas.0609650104;
RA   Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X.,
RA   Han W., Peng X., Liu R., Wang L.;
RT   "Genome and proteome of long-chain alkane degrading Geobacillus
RT   thermodenitrificans NG80-2 isolated from a deep-subsurface oil
RT   reservoir.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).
CC   -!- FUNCTION: Is involved in L-lactate degradation and allows cells to
CC       grow with lactate as the sole carbon source. Has probably a role
CC       as an electron transporter during oxidation of L-lactate.
CC       {ECO:0000255|HAMAP-Rule:MF_02103}.
CC   -!- SIMILARITY: Belongs to the LutB/YkgF family. {ECO:0000255|HAMAP-
CC       Rule:MF_02103}.
DR   EMBL; CP000557; ABO65749.1; -; Genomic_DNA.
DR   RefSeq; WP_008881225.1; NC_009328.1.
DR   ProteinModelPortal; A4IK95; -.
DR   SMR; A4IK95; -.
DR   STRING; 420246.GTNG_0367; -.
DR   PRIDE; A4IK95; -.
DR   EnsemblBacteria; ABO65749; ABO65749; GTNG_0367.
DR   GeneID; 31759613; -.
DR   KEGG; gtn:GTNG_0367; -.
DR   eggNOG; ENOG4107QR9; Bacteria.
DR   eggNOG; COG1139; LUCA.
DR   HOGENOM; HOG000262102; -.
DR   KO; K18929; -.
DR   OMA; HCPVYDK; -.
DR   OrthoDB; 688908at2; -.
DR   BioCyc; GTHE420246:G1G82-429-MONOMER; -.
DR   Proteomes; UP000001578; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019516; P:lactate oxidation; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10420; -; 1.
DR   HAMAP; MF_02103; LutB; 1.
DR   InterPro; IPR004452; 4Fe-4S-bd.
DR   InterPro; IPR024569; 4Fe-4S-bd_C.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR024185; FTHF_cligase-like_sf.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR003741; LUD_dom.
DR   InterPro; IPR022825; LutB.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR32479:SF10; PTHR32479:SF10; 1.
DR   Pfam; PF11870; DUF3390; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   Pfam; PF02589; LUD_dom; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   SUPFAM; SSF46548; SSF46548; 1.
DR   TIGRFAMs; TIGR00273; TIGR00273; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Complete proteome; Electron transport; Iron; Iron-sulfur;
KW   Metal-binding; Repeat; Transport.
FT   CHAIN         1    476       Lactate utilization protein B.
FT                                /FTId=PRO_0000383983.
FT   DOMAIN      304    334       4Fe-4S ferredoxin-type 1.
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   DOMAIN      353    382       4Fe-4S ferredoxin-type 2.
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       313    313       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       316    316       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       319    319       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       323    323       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       366    366       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       369    369       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
FT   METAL       373    373       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_02103}.
SQ   SEQUENCE   476 AA;  53122 MW;  7B37FE54062812E3 CRC64;
     MPMKIENGPF WKRVEENLQN DFMRGAVAGM QDRGYVRRLG VIEELGHWEE WRSLAEQIRK
     HTLENLDYYL MQLSENVAKR GGHVFFAQTA EEANDYIRRI ALEKQAKKIV KSKSMVTEEI
     NLNPVLEAIG CDVVETDLGE YILQIDDHDP PSHIVGPALH KNKEQIRDVF HRKLGYNKSS
     DPVELARHAR ETLRRDYLTA DIGITGCNFA IAESGSITLV TNEGNADLVT SLPKTQITVM
     GMERIVPTFK EMEVLVSMLT RSAVGQKLTS YITVLTGPRE QGDADGPEEF HLVIVDNGRS
     SILGTEFQPV LQCIRCAACV NVCPVYRHIG GHSYGSIYSG PIGAVLSPLL GGYDDYKELP
     YASSLCAACT EVCPVKIPLH ELLIKHRQII VEREGKAPVA EKLAMKAFRL GTASPSLYRF
     GTKLAPSAFA PFAEDGRITK GPGPLKAWTE SRVFPAPNNE RFRDWFRNRQ KGGNPS
//
DBGET integrated database retrieval system