ID   A4IP19_GEOTN            Unreviewed;      1386 AA.
AC   A4IP19;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=TPR-repeat-containing protein {ECO:0000313|EMBL:ABO67073.1};
GN   OrderedLocusNames=GTNG_1709 {ECO:0000313|EMBL:ABO67073.1};
OS   Geobacillus thermodenitrificans (strain NG80-2).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=420246 {ECO:0000313|EMBL:ABO67073.1, ECO:0000313|Proteomes:UP000001578};
RN   [1] {ECO:0000313|EMBL:ABO67073.1, ECO:0000313|Proteomes:UP000001578}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NG80-2 {ECO:0000313|EMBL:ABO67073.1,
RC   ECO:0000313|Proteomes:UP000001578};
RX   PubMed=17372208; DOI=10.1073/pnas.0609650104;
RA   Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X.,
RA   Han W., Peng X., Liu R., Wang L.;
RT   "Genome and proteome of long-chain alkane degrading Geobacillus
RT   thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).
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DR   EMBL; CP000557; ABO67073.1; -; Genomic_DNA.
DR   RefSeq; WP_011887487.1; NC_009328.1.
DR   KEGG; gtn:GTNG_1709; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG3071; Bacteria.
DR   eggNOG; COG3271; Bacteria.
DR   HOGENOM; CLU_259992_0_0_9; -.
DR   Proteomes; UP000001578; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd02549; Peptidase_C39A; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR   InterPro; IPR005074; Peptidase_C39.
DR   InterPro; IPR039564; Peptidase_C39-like.
DR   InterPro; IPR039563; Peptidase_C39_single_dom.
DR   InterPro; IPR006597; Sel1-like.
DR   InterPro; IPR011717; TPR-4.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR013105; TPR_2.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45586:SF1; SLR0626 PROTEIN; 1.
DR   PANTHER; PTHR45586; TPR REPEAT-CONTAINING PROTEIN PA4667; 1.
DR   Pfam; PF13529; Peptidase_C39_2; 1.
DR   Pfam; PF13429; TPR_15; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   Pfam; PF14559; TPR_19; 2.
DR   Pfam; PF07719; TPR_2; 1.
DR   Pfam; PF07721; TPR_4; 2.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00671; SEL1; 2.
DR   SMART; SM00028; TPR; 12.
DR   SUPFAM; SSF48452; TPR-like; 4.
DR   PROSITE; PS50990; PEPTIDASE_C39; 1.
DR   PROSITE; PS50005; TPR; 5.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   4: Predicted;
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          313..439
FT                   /note="Peptidase C39"
FT                   /evidence="ECO:0000259|PROSITE:PS50990"
FT   REPEAT          561..594
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          731..764
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          906..939
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          1002..1035
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          1036..1069
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   1386 AA;  160767 MW;  9B658DC21DF86D59 CRC64;
     MNHIEHIASL VEEKRIVDAL AEVRPQLEKV GLFGWRSLLA SWDSIEPFRA LIRLFDYALM
     YRHSGLIARY AHRKLNTLQT LAWVCDEWLE NRRPLDVEEA LLPRLAKALQ GKTDEPDEAI
     ARAAFTLVRA LLDMRRVDEA REWMNVVARY ETVSIHDKWG YFYIETGDRK RAEQVIRSGL
     DDSERGDMCY LLLADLYALD GRHHEALAVL EEGRRRFPQV LSFYAERVRR LRDVRAYREA
     LAAMEELDRL NPLHMHRRYF AHVRAELYYQ LEEWEKLESL VRAEPRLEKT PYARALGRQR
     ERAVVLPLVS VVQKHNYCVP ASLEMMLRLL GSPRTQDEVA EHIFDVRGSK LSTTVHYLEK
     LGFVCRFFIG SPPHWKRLID EGIPVLLSVD YEQSSHVQVL FGYDERLGAF YVQDPNVFEP
     FVVPEEELEK WYAGTHYLSI VALPREKVAL AAELPIEEDR YFRELHAFAE KMDEDEQAYF
     DAFVAFLRQH EHIPYTWLYT VKHFGSDEAK TLVLDYAERV LERYPEHNDL LLVTAKAYVY
     IQEMERAEQA LKQAKGKRQS PLYHYLRGRI AFFMSRYEEA VRHFRASLQL DPDQPEVWSY
     TALASAYAGY TERGLVCSRI AVHLHPGDLF IETNHGLLLF HAKRLAEARK WFDHLVRRER
     RDAHLWYERA RCDLELGHRR KAERGFRVAK ALDPREPYPY VMLADLYDDD GKREQAKAVL
     KEGLAAAERL ALLYVRLGDA YMDEGEVEQA ASCYEKAIRH DDNDVFAHLG LASALMERGH
     VEAAKRHVME QRTRFADDSE YWLNAGKWLL VHGVANEAEG KQLALSWLEN GLRLAEFDIE
     EVYEFYIDQL TTPALRERGR TFLEQLIAAR PGLAPAHSAL GVLYERQSRP SKAMAVYRKA
     AAMGHPLSLY RLAELCSALG RYEEAKQHYE SCLDADPSFA LCHFRLAALY EMEGNEEQQH
     AHLLEAVRLA PLRADIESLA ALLEPSALLQ ALADARRLAG DVWYYDSLGY VYGALGREDQ
     EKMAVEKALA LEPDHREALR HYANVLHQEG RTKEAIELFE RLMMHHPDDE SLYSAYVALF
     PKTMRGLGKL RHRLERLTID RQEKSVVYRN AAAALLPYLE GERNKNEAGA RWWTKAKQWV
     GRVSVLSIAM DLYEEAIHLD RGHHEAYGQL ARLYAAAELE GDAVKMWRKA LANVWDPSLA
     REFVEYLLAA DDVRKRQEAQ SWLDRLLTDE PDDLELLTWQ AVIWLKSGQQ EKAERQLQVI
     VAEEPLAREA FMLLSEQYME TGRYAEAAAL WEHCAHWYAE DTEWHLQLAA IYEEMGHLNQ
     ALATIERHAH VSEDIRLRYE RARYLSLLGR FDEAKQELDA VWAADESGEF AALAAEEPAF
     HRMKQM
//