ID A4J807_DESRM Unreviewed; 207 AA.
AC A4J807;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:ABO51210.1};
DE EC=5.4.1.2 {ECO:0000313|EMBL:ABO51210.1};
GN OrderedLocusNames=Dred_2706 {ECO:0000313|EMBL:ABO51210.1};
OS Desulforamulus reducens (strain ATCC BAA-1160 / DSM 100696 / MI-1)
OS (Desulfotomaculum reducens).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=349161 {ECO:0000313|EMBL:ABO51210.1, ECO:0000313|Proteomes:UP000001556};
RN [1] {ECO:0000313|EMBL:ABO51210.1, ECO:0000313|Proteomes:UP000001556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MI-1 {ECO:0000313|EMBL:ABO51210.1,
RC ECO:0000313|Proteomes:UP000001556};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Kim E., Tebo B.M., Richardson P.;
RT "Complete sequence of Desulfotomaculum reducens MI-1.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP000612; ABO51210.1; -; Genomic_DNA.
DR RefSeq; WP_011879007.1; NC_009253.1.
DR AlphaFoldDB; A4J807; -.
DR STRING; 349161.Dred_2706; -.
DR KEGG; drm:Dred_2706; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_1_1_9; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000001556; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABO51210.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001556}.
FT DOMAIN 12..205
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 207 AA; 22291 MW; 5D4706BF47C00D2A CRC64;
MSFKDVIWQP QEIERESMRQ VAEFLLPLNL TPGEKAVVGR IIHTSGDPDL GAQVRFHPQA
VVKGLEALQA GVDIYTDVTM LQAGINSRRL AELGGQVHCA VHSLEVVEEA RERGITRSAV
AMERFGNRLN GQVVAIGNAP TALFALMRMI KEGLQPALVV GMPVGFVGAA HSKELLSQMD
VPNITLLGTR GGSPLAAATI NALLYYK
//
