ID   A4JG33_BURVG            Unreviewed;      1394 AA.
AC   A4JG33;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:ABO55236.1};
GN   OrderedLocusNames=Bcep1808_2234 {ECO:0000313|EMBL:ABO55236.1};
OS   Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia
OS   (strain R1808)).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=269482 {ECO:0000313|EMBL:ABO55236.1, ECO:0000313|Proteomes:UP000002287};
RN   [1] {ECO:0000313|Proteomes:UP000002287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G4 / LMG 22486 {ECO:0000313|Proteomes:UP000002287};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia vietnamiensis G4.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000614; ABO55236.1; -; Genomic_DNA.
DR   KEGG; bvi:Bcep1808_2234; -.
DR   eggNOG; COG1643; Bacteria.
DR   HOGENOM; CLU_001832_3_3_4; -.
DR   Proteomes; UP000002287; Chromosome 1.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:ABO55236.1};
KW   Helicase {ECO:0000313|EMBL:ABO55236.1};
KW   Hydrolase {ECO:0000313|EMBL:ABO55236.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:ABO55236.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002287}.
FT   DOMAIN          104..271
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          320..487
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1067..1103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..55
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1394 AA;  155073 MW;  58DA673F879C3974 CRC64;
     MSNVPKSPAP TRANADPAQH PDGAADARQQ PGRQQQTRQG GKPPRDDERR RDAGQPAAPA
     TRAADGERTP RRERAPRAPI APNPVPKISY PESLPVSGRR DEIARAIAAH QVVIVCGETG
     SGKTTQLPKI CLGLGRGLGA GGTGLIGHTQ PRRLAASSTG RRIAEELGTP FGEVVGYKVR
     FTDNLAPGAS VKLMTDGILL AETQNDPLLK AYDTLIIDEA HERSLNIDFL LGYLKEILPR
     RPDLKLIVTS ATIDADRFAR HFGSDARPAP VIEVSGRLYP VEVRYRPVAE DRPAVKNAEG
     TGGRDRVKTA REAERDLMDA IVDAVDELCR EGPGDVLVFL PGEREIRDAA EALRKHHPPH
     TEILPLFARL SAADQDKVFK ASNARRIVLA TNVAETSLTV PGIRYVVDTG LARVKRYSYR
     NKVEQLQVES ISQAAANQRA GRCGRVADGI CIRLYEESDF QARARFTDPE ILRSSLAAVI
     LRMKSLHLTA IESFPFLEPP PGRAIADGYQ LLNELGAVDD DNALTPLGRE LARLPLDPRV
     GRMILAARDQ QALREVLIIA SALSVQDPRD RPSDAQEQAD QAHRRFADER SEFLQWLKIW
     AWFEEAVAHK KSNRQLIDAC RQNFLSHLRL REWRDVHSQL LTVVREHGWR LNEAEATYEQ
     IHLALLTGLL GNLGLKADDD PHYLGARGIK FYLWPGSALA KKAGRWVMAA ELVETSRLYA
     RCLAKIEPEW VEKVGAHLLK KSLSEPHWEK RPAQVSAFER ATLYGLPIYH RRRVAFGRQD
     PARARELFIR GALVEGEFDT RLPFFAHNRK LLADIEQLEH KSRRQDVLVD DELIYAYYDQ
     AIPQGIHTGA AFERWYRDEV KKGGQPEDKQ RLLYLSRDDL MRHEAAGVTT ELFPKRMTMA
     GVEMALTYHF EPGTPRDGVT LAVPLYALNQ VDARRCEWLV PGMLKEKVQL LLKSLPQKLR
     RHCVPLPEYA AGFVERMGRE RFGAGGLVDA LIADVRGETQ VAMKTADFKL ETLPAHLFMN
     FKVIDEHGRQ LAMGRNLAQL RQELGAQAQQ QFQKIAAASS IAASGDAAGD APAGASAPGG
     AGAAGALAKG GKPARGAAPH TAAPAEAGAT ALYENLTTWN FGKLPELLEI RRRGQTLYGY
     PALVDRGTHC DVEVFDSPEE AARIHRAGLR RLFALQLKEP IKFLEKNLPG LREMAMQYMS
     LGTQDELRDQ LIDTALDRAC LQEPLPDDDA SFHARRDEGR SRLNLLAQEI ARLVAQILAE
     YAGLAKKLAQ AKPFAQAHAD LQQQLAALVG KRFVIDTPYV QLAHFPRYLK GIALRIDKLK
     ADPARDAKQF AELQPLVQQY QRAVSQRGGV VDPRLAEFRW LLEELRISLF AQELRTPMPV
     SVKRLHKVWE SMQR
//