ID A4KUC3_STRHI Unreviewed; 538 AA.
AC A4KUC3;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Carbamoyltransferase {ECO:0000313|EMBL:SHF86147.1};
DE SubName: Full=TlmD {ECO:0000313|EMBL:ABL74951.1};
GN Name=tlmD {ECO:0000313|EMBL:ABL74951.1};
GN ORFNames=SAMN05444320_105261 {ECO:0000313|EMBL:SHF86147.1};
OS Streptoalloteichus hindustanus.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Streptoalloteichus.
OX NCBI_TaxID=2017 {ECO:0000313|EMBL:ABL74951.1};
RN [1] {ECO:0000313|EMBL:ABL74951.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 31158 {ECO:0000313|EMBL:ABL74951.1};
RX PubMed=17216057; DOI=10.1039/b615284h;
RA Tao M., Wang L., Wendt-Pienkowski E., George N.P., Galm U., Zhang G.,
RA Coughlin J.M., Shen B.;
RT "The tallysomycin biosynthetic gene cluster from Streptoalloteichus
RT hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis
RT of the bleomycin family of antitumor antibiotics.";
RL Mol. Biosyst. 3:60-74(2007).
RN [2] {ECO:0000313|EMBL:SHF86147.1, ECO:0000313|Proteomes:UP000184501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44523 {ECO:0000313|EMBL:SHF86147.1,
RC ECO:0000313|Proteomes:UP000184501};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NodU/CmcH family.
CC {ECO:0000256|ARBA:ARBA00006129}.
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DR EMBL; EF032505; ABL74951.1; -; Genomic_DNA.
DR EMBL; FQVN01000005; SHF86147.1; -; Genomic_DNA.
DR RefSeq; WP_073484948.1; NZ_FQVN01000005.1.
DR AlphaFoldDB; A4KUC3; -.
DR STRING; 2017.SAMN05444320_105261; -.
DR OrthoDB; 9780777at2; -.
DR Proteomes; UP000184501; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 3.90.870.20; Carbamoyltransferase, C-terminal domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR031730; Carbam_trans_C.
DR InterPro; IPR038152; Carbam_trans_C_sf.
DR InterPro; IPR003696; Carbtransf_dom.
DR PANTHER; PTHR34847; NODULATION PROTEIN U; 1.
DR PANTHER; PTHR34847:SF1; NODULATION PROTEIN U; 1.
DR Pfam; PF16861; Carbam_trans_C; 1.
DR Pfam; PF02543; Carbam_trans_N; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000184501};
KW Transferase {ECO:0000313|EMBL:SHF86147.1}.
FT DOMAIN 13..201
FT /note="Carbamoyltransferase"
FT /evidence="ECO:0000259|Pfam:PF02543"
FT DOMAIN 241..314
FT /note="Carbamoyltransferase"
FT /evidence="ECO:0000259|Pfam:PF02543"
FT DOMAIN 369..535
FT /note="Carbamoyltransferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16861"
SQ SEQUENCE 538 AA; 59520 MW; C02B966A1BB3E204 CRC64;
MSVERVRTIL SVNFNHDGSA VVLSEGRIRG YVNTERFSRI KKHPGLRAAD LAEVLDQAGV
ELADVDHVLL CNLHNMDSPD VVRLHGSDLK DTWFEFWLNQ RNTEVRIDGR RIPCTVNPDH
HLIHAATAYF TSPFESGAAL AIDPTGCRAF LGRDNKLFPL RRDYDKWFNA NFGYCSVSEL
MFGSSIVGAG KVMGLSPYGR PTGEVEPPPD SMVDFEELVR FADRDPVPVQ VGDRTLNAAL
AYYIQLGLER QMVRLFTDLA PLCRRNGINP DICLSGGTAL NAIATQLAFA GSGFERIHFH
PACGDDGTAI GAALWYWHHV LGNPRLPHDN AGLMYSVRTY DQRAVDRALT AHADRLVVES
VPDYVGKTAE LLAGGAVVGW WDGASEVGPR ALGHRSILAD PRDPTMRDRL NSRVKFREHF
RPFAPSVLNE RATEWFGLCD SPFMLRAAPV QRASEVPAIT HIDGTSRLQT VSRVDNPAFY
DLIAAFEDRT GIPMVLNTSL NTKGEPIVET PDDAVRTLLG CELDYLVLPH TLVSRRGA
//
