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Database: UniProt
Entry: A4QX49
LinkDB: A4QX49
Original site: A4QX49 
ID   DBP7_MAGO7              Reviewed;         825 AA.
AC   A4QX49; G4N0I4;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   16-OCT-2019, entry version 78.
DE   RecName: Full=ATP-dependent RNA helicase DBP7;
DE            EC=3.6.4.13;
GN   Name=DBP7; ORFNames=MGG_05810;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice
OS   blast fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Magnaporthales; Pyriculariaceae;
OC   Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W.,
RA   Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J.,
RA   Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: ATP-binding RNA helicase involved in the biogenesis of
CC       60S ribosomal subunits and is required for the normal formation of
CC       25S and 5.8S rRNAs. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC       box family of RNA helicases and controls ATP binding and
CC       hydrolysis.
CC   -!- MISCELLANEOUS: Present with 1460 molecules/cell in log phase SD
CC       medium.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX31/DBP7
CC       subfamily. {ECO:0000305}.
DR   EMBL; CM001233; EHA52318.1; -; Genomic_DNA.
DR   RefSeq; XP_003712125.1; XM_003712077.1.
DR   STRING; 318829.MGG_05810T0; -.
DR   EnsemblFungi; MGG_05810T0; MGG_05810T0; MGG_05810.
DR   GeneID; 2684165; -.
DR   KEGG; mgr:MGG_05810; -.
DR   EuPathDB; FungiDB:MGG_05810; -.
DR   InParanoid; A4QX49; -.
DR   KO; K14806; -.
DR   OMA; FSRIQWL; -.
DR   OrthoDB; 973872at2759; -.
DR   Proteomes; UP000009058; Chromosome 3.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR025313; DUF4217.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF13959; DUF4217; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01178; DUF4217; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase;
KW   Nucleotide-binding; Nucleus; Reference proteome; Ribosome biogenesis;
KW   RNA-binding; rRNA processing.
FT   CHAIN         1    825       ATP-dependent RNA helicase DBP7.
FT                                /FTId=PRO_0000294643.
FT   DOMAIN      164    373       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      400    625       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     177    184       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       131    160       Q motif.
FT   MOTIF       302    305       DEAD box.
SQ   SEQUENCE   825 AA;  89217 MW;  6F4FE8EFBCB786E3 CRC64;
     MDDDGLLINF EVGEGPIKPQ IKFTGGRWRE RNRLQRSVKR GLTGSQSNDA VADDVGPAPA
     KRQRLSEGAA PEIQRRFRPQ AQGPRSQHVS SRLFTSNPTP VTNFDEPETA PAEEPAEPAL
     PSNAPLSDEA ATFAALGLSR RIAQHLSAKL ELKAPTAIQH RAVPHLVTTD EDAFLQAQTG
     SGKTLAYLLP IVNRILALNQ NEDGTISKDA SKKIHRNSGL LAIVLAPTRE LCKQIATVLE
     KLLRCAPWIV STTVIGGESK HSEKARIRKG INILIATPGR LKDHLDNTKV LDVSLARWLI
     LDEGDRMMEM GFMDDLKEIV SKMREAPLKK INPDGIQLEP ALPTRRVTVL CSATLDHAQV
     RRLGEYSLEA DKTELIKVDG TEAAKEGDEA SEAVFAAPSQ LKQSYLVVPA KLRLVTLIAL
     LKSSFARRGS VMKAIIFISC ADSVDFHFDL LRSPIKEPKE AAAPPTPKKA PKDAGETPDT
     PPKETKPTKP VTNHTESTVG KACYITSAAN TTITLHKLHG SLAQPVRTAT LDSFSKSKDP
     SILITTDISS RGLDVPAVDL VIEYDPAFAV ADHVHRIGRT ARAGRPGKAV LFLQPGSEEG
     YVGLLQKNAS TALTPQLYDS VLQAGFSSNI DLPPVTATNE DGQDTEQQKQ LDSRKQTWTS
     RAEALQLHLE QRLLASDASS QASNNSGKGF NSKKGASTKL GKPAPKSSDG ATGTLLASGR
     QAFRSHIRAY ATHVRDERVY FDMTQLHLGH MAKAFGLREA PGGIGAGVQR RTVKPSAANG
     GGKKSTKGDD GDGLDKQDDD EAERTRRMKK MMRMVGAGAS EFNIG
//
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