ID   CIAO1_PYRO7             Reviewed;         446 AA.
AC   A4R7U3; G4NAT4;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   24-JAN-2024, entry version 96.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=CIA1 {ECO:0000255|HAMAP-Rule:MF_03037}; ORFNames=MGG_03150;
OS   Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Magnaporthe oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
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DR   EMBL; CM001234; EHA50526.1; -; Genomic_DNA.
DR   RefSeq; XP_003716845.1; XM_003716797.1.
DR   AlphaFoldDB; A4R7U3; -.
DR   SMR; A4R7U3; -.
DR   STRING; 242507.A4R7U3; -.
DR   GeneID; 2676736; -.
DR   KEGG; mgr:MGG_03150; -.
DR   VEuPathDB; FungiDB:MGG_03150; -.
DR   eggNOG; KOG0645; Eukaryota.
DR   HOGENOM; CLU_000288_57_8_1; -.
DR   InParanoid; A4R7U3; -.
DR   OMA; IREIRWS; -.
DR   OrthoDB; 5486866at2759; -.
DR   Proteomes; UP000009058; Chromosome 4.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19920:SF0; CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED; 1.
DR   PANTHER; PTHR19920; WD40 PROTEIN CIAO1; 1.
DR   Pfam; PF00400; WD40; 5.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..446
FT                   /note="Probable cytosolic iron-sulfur protein assembly
FT                   protein 1"
FT                   /id="PRO_0000382518"
FT   REPEAT          17..59
FT                   /note="WD 1"
FT   REPEAT          63..106
FT                   /note="WD 2"
FT   REPEAT          143..182
FT                   /note="WD 3"
FT   REPEAT          192..241
FT                   /note="WD 4"
FT   REPEAT          247..291
FT                   /note="WD 5"
FT   REPEAT          330..368
FT                   /note="WD 6"
FT   REPEAT          398..446
FT                   /note="WD 7"
FT   REGION          106..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   446 AA;  49030 MW;  9EF6DD70303A75AA CRC64;
     MPARAAGAGV ELSRLSAFKP DLYHRAWSSI PHPTLPLIAT AHEKSVTVFS LSTLSAHSNL
     TGGHTRSVRC AVWKPNLPSG KLCLVTASFD STAGLWRWEG DVPLEEGTKK GESTEIDVTR
     RRNNNDSDKD NDDDWEFTLV LEGHENEIKS AAFSPSGQYL ATCSRDKSIW IWEDVGANEG
     DDEWETVAVL TEHDGDVKCV AWCPDVPGRN ISSYSPDVLA SASYDDTIRI WREDGDGEWA
     CVAVLEGHSS TVWGVQWEPK VDNTKFPRLI SWSADKTIRV WTLEQDDPEA SLSQPGAVQS
     PFKSGLGGIP NTMRRTLKEE WRCSAVLPSV HTRDIYSASW SKNGRVASTG SDGSILVYEE
     CAPSNPSTTP ADLEEGDSNV IVKPGEAKWK VLGKVSDGHG PYEINHITWC SRYDAGVEQR
     GVEEMLVTTG DDGIVQAWQL KESIEL
//