ID A4RVL2_OSTLU Unreviewed; 560 AA.
AC A4RVL2;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
GN ORFNames=OSTLU_31014 {ECO:0000313|EMBL:ABO95731.1};
OS Ostreococcus lucimarinus (strain CCE9901).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Ostreococcus.
OX NCBI_TaxID=436017 {ECO:0000313|EMBL:ABO95731.1, ECO:0000313|Proteomes:UP000001568};
RN [1] {ECO:0000313|EMBL:ABO95731.1, ECO:0000313|Proteomes:UP000001568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCE9901 {ECO:0000313|EMBL:ABO95731.1,
RC ECO:0000313|Proteomes:UP000001568};
RX PubMed=17460045; DOI=10.1073/pnas.0611046104;
RA Palenik B., Grimwood J., Aerts A., Rouze P., Salamov A., Putnam N.,
RA Dupont C., Jorgensen R., Derelle E., Rombauts S., Zhou K., Otillar R.,
RA Merchant S.S., Podell S., Gaasterland T., Napoli C., Gendler K.,
RA Manuell A., Tai V., Vallon O., Piganeau G., Jancek S., Heijde M.,
RA Jabbari K., Bowler C., Lohr M., Robbens S., Werner G., Dubchak I.,
RA Pazour G.J., Ren Q., Paulsen I., Delwiche C., Schmutz J., Rokhsar D.,
RA Van de Peer Y., Moreau H., Grigoriev I.V.;
RT "The tiny eukaryote Ostreococcus provides genomic insights into the paradox
RT of plankton speciation.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7705-7710(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU004914}.
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DR EMBL; CP000584; ABO95731.1; -; Genomic_DNA.
DR RefSeq; XP_001417438.1; XM_001417401.1.
DR AlphaFoldDB; A4RVL2; -.
DR EnsemblPlants; ABO95731; ABO95731; OSTLU_31014.
DR GeneID; 5001417; -.
DR Gramene; ABO95731; ABO95731; OSTLU_31014.
DR KEGG; olu:OSTLU_31014; -.
DR eggNOG; KOG1347; Eukaryota.
DR HOGENOM; CLU_012893_16_3_1; -.
DR OMA; SFPFAHR; -.
DR OrthoDB; 36275at2759; -.
DR Proteomes; UP000001568; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13136; MATE_DinF_like; 1.
DR InterPro; IPR044644; DinF-like.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR42893:SF55; DNA DAMAGE-INDUCIBLE PROTEIN F; 1.
DR PANTHER; PTHR42893; PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Reference proteome {ECO:0000313|Proteomes:UP000001568};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 216..237
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 398..417
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
SQ SEQUENCE 560 AA; 58948 MW; C603BACB8A3A1B91 CRC64;
MPTARPRATD DATARDARTR ARRTILGVDR ATGEAIPDWD ECAEWRARAP PSAETLELLD
ASIFALALPG VAELLLDPVM GAVDTAFIGR LTGDGAAEAL GGLAVSTTCF TFCFKLFNFL
AVVTGPLVAA KISASGGRDS AEGRRAAKKT VGSAMALALA LGFATMGIME VFTDDLLAFC
GASHEALLNP SEDLLPDADV PTIKGMLEYG EDYLRIRAAS LPACLIVMVG VGAFRGLLDT
RTPLYVAVVT EIFHLGLDPF LIYGIGPFPA FDVAGAATAT TVAEWVGAIW FWKLMMDEEI
LDFQSVFRLP DESNDDLGTL VSGSTSQLAR TVLLQTVLVR ATSTAAMLGA AGAHQVCLQA
WWVTLFGLDS VAVSAQALVA ASLGKNDVPG ARIAADRALS WGVGAGVLVG VVVFLSADQL
PYIFTNDAEI AAQAATPIRI LSLLQPLNSA VFVGDGVFQG SADFDFLAKA MAISAGGGIL
ALTAAGQMEG ASLTSVWLGM ATLMFGRAAT LGWRYFKDDE SPLYVTPFEC AVYYDDLPSV
DVDFVDVDAK VSKDETTKPR
//
