ID A4S315_OSTLU Unreviewed; 802 AA.
AC A4S315;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Rab-GAP TBC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=OSTLU_25081 {ECO:0000313|EMBL:ABO97928.1};
OS Ostreococcus lucimarinus (strain CCE9901).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Ostreococcus.
OX NCBI_TaxID=436017 {ECO:0000313|EMBL:ABO97928.1, ECO:0000313|Proteomes:UP000001568};
RN [1] {ECO:0000313|EMBL:ABO97928.1, ECO:0000313|Proteomes:UP000001568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCE9901 {ECO:0000313|EMBL:ABO97928.1,
RC ECO:0000313|Proteomes:UP000001568};
RX PubMed=17460045; DOI=10.1073/pnas.0611046104;
RA Palenik B., Grimwood J., Aerts A., Rouze P., Salamov A., Putnam N.,
RA Dupont C., Jorgensen R., Derelle E., Rombauts S., Zhou K., Otillar R.,
RA Merchant S.S., Podell S., Gaasterland T., Napoli C., Gendler K.,
RA Manuell A., Tai V., Vallon O., Piganeau G., Jancek S., Heijde M.,
RA Jabbari K., Bowler C., Lohr M., Robbens S., Werner G., Dubchak I.,
RA Pazour G.J., Ren Q., Paulsen I., Delwiche C., Schmutz J., Rokhsar D.,
RA Van de Peer Y., Moreau H., Grigoriev I.V.;
RT "The tiny eukaryote Ostreococcus provides genomic insights into the paradox
RT of plankton speciation.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7705-7710(2007).
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DR EMBL; CP000589; ABO97928.1; -; Genomic_DNA.
DR RefSeq; XP_001419635.1; XM_001419598.1.
DR AlphaFoldDB; A4S315; -.
DR STRING; 436017.A4S315; -.
DR EnsemblPlants; ABO97928; ABO97928; OSTLU_25081.
DR GeneID; 5003841; -.
DR Gramene; ABO97928; ABO97928; OSTLU_25081.
DR KEGG; olu:OSTLU_25081; -.
DR eggNOG; KOG2058; Eukaryota.
DR HOGENOM; CLU_351046_0_0_1; -.
DR OMA; DHRAEIW; -.
DR OrthoDB; 616243at2759; -.
DR Proteomes; UP000001568; Chromosome 9.
DR GO; GO:0005768; C:endosome; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR22957:SF687; TBC (TRE-2_BUB2_CDC16) DOMAIN FAMILY; 1.
DR PANTHER; PTHR22957; TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001568}.
FT DOMAIN 140..364
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 658..773
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 57..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 88078 MW; 74D781108FE61896 CRC64;
MSPVRASTKL ATRARYAAID EDAGEEDAAS FVDADDRMPF GRASDFPPSY GEAKALKRVE
GEASVSGEPS SEEEDLEAAT PRDELGFEVP ESLRETHEAR RAVRADHRIR QMEYLEVYRN
VPEKQRGVGG DACLALAVNG IHPDHRAEIW AEKLKAHVKQ YSSSHSFYQY LELGQASLSD
AERELIEGDV RAACPTHPLL RSDVAESTSR STSSSFTHAF ANTASEGFVL GGKGVAFQDF
PRTLINILIA AAERSPHGYC SGFVVPAAVM LLLTEDEEAS FWMLAGFTED VLSSVISRSC
INLYAEAKYI DLDVMLHEPE LAAHLNEGDC RPSVVVAGLL TRVGLGVLPT ESVLRLWDAL
ILEGGQVLAP FSILVMKAAK EQLLAAAVGD LCETFDAEAA RMHDVGDTLM DAIVASREMS
SKFDSLSIRL GEREVTADVL NNLFNFRDVV RSLSESAGPE GIGRQEIITR EELEEVVCAT
YCLEQFTDVD TAVDKKYQSR ELLMAYDLAV RHKEELKTKG LRFDEFMKVL RVKSSTSSKL
KMLAVKGDTV EARVKNFIIG ETNDGMPTEK SVKLALFVAN GVIPTQRLSS APVESKILNG
LASSENWYCE MRMNARAALI LANFAIPLFI TEDAVPSMER DDASDSKDAF DVSIIASKAK
ALDDSPRAFG GLVPLAHTEY HILVQTREGP PRVVKKRFSD FKSLHEELRK SGCYNVTRVA
ENAIGTDAAL SVDPHVVASR SVSLQRYLDQ LNACGLPKVH RFLRAFLGLD EPKSRVSRLR
SLCAACSPAR IVCGFTARAR RR
//
