ID A4SX86_POLAQ Unreviewed; 582 AA.
AC A4SX86;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Dihydroxyacid dehydratase {ECO:0000313|EMBL:ABP34100.1};
DE EC=4.2.1.9 {ECO:0000313|EMBL:ABP34100.1};
GN OrderedLocusNames=Pnuc_0884 {ECO:0000313|EMBL:ABP34100.1};
OS Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 /
OS QLW-P1DMWA-1) (Polynucleobacter necessarius subsp. asymbioticus).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Polynucleobacter.
OX NCBI_TaxID=312153 {ECO:0000313|EMBL:ABP34100.1, ECO:0000313|Proteomes:UP000000231};
RN [1] {ECO:0000313|EMBL:ABP34100.1, ECO:0000313|Proteomes:UP000000231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18221 / CIP 109841 / QLW-P1DMWA-1
RC {ECO:0000313|Proteomes:UP000000231};
RX PubMed=22675600; DOI=10.4056/sigs.2395367;
RA Meincke L., Copeland A., Lapidus A., Lucas S., Berry K.W., Del Rio T.G.,
RA Hammon N., Dalin E., Tice H., Pitluck S., Richardson P., Bruce D.,
RA Goodwin L., Han C., Tapia R., Detter J.C., Schmutz J., Brettin T.,
RA Larimer F., Land M., Hauser L., Kyrpides N.C., Ivanova N., Goker M.,
RA Woyke T., Wu Q.L., Pockl M., Hahn M.W., Klenk H.P.;
RT "Complete genome sequence of Polynucleobacter necessarius subsp.
RT asymbioticus type strain (QLW-P1DMWA-1(T)).";
RL Stand. Genomic Sci. 6:74-83(2012).
CC -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC {ECO:0000256|ARBA:ARBA00006486}.
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DR EMBL; CP000655; ABP34100.1; -; Genomic_DNA.
DR RefSeq; WP_011902725.1; NC_009379.1.
DR AlphaFoldDB; A4SX86; -.
DR GeneID; 31481248; -.
DR KEGG; pnu:Pnuc_0884; -.
DR eggNOG; COG0129; Bacteria.
DR HOGENOM; CLU_014271_3_0_4; -.
DR Proteomes; UP000000231; Chromosome.
DR GO; GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR InterPro; IPR042096; Dihydro-acid_dehy_C.
DR InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR InterPro; IPR037237; IlvD/EDD_N.
DR PANTHER; PTHR43183:SF1; HYPOTHETICAL DIHYDROXY-ACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00920; ILVD_EDD; 1.
DR SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR PROSITE; PS00886; ILVD_EDD_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:ABP34100.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000231}.
SQ SEQUENCE 582 AA; 61914 MW; D2BD31ED87B0F791 CRC64;
MSSKPNDSKN GTETGLRKGL TSYGDKGFSL FLRKAFIKGA GYTNSALDRP VIGIINTGSA
YNPCHGNMPQ LLEAVKRGVM LAGGLPMEFP TISIHESFAA PTSMYLRNLM SMDTEEMLRA
QPMDAVVMIG GCDKTVPAQM MGAASAGLPA IQLITGSMLT GSHRNERVGA CTDCRRYWGK
FRAGEIDEIE KDEVNDQLVA SVGTCSVMGT ASTMACIAEA LGMTVPGGAT PPAVTADRIR
VAEETGTCAV KMAKEGLTID KILTADAFEN AMRVLLAIGG STNGIVHLAA IAGRMGLEID
LDALDKMGNE TPVLVDLKPS GDHYMENFHD AGGMTALLRE LKPLLKLDAL TVSGRTLGEE
IDAGPPSFKQ DVVRKIDNPI YPRGSIAVLH GNLAPGGAII KQSAANEKLM EHEGRAVVFE
NSEDLANRID SLDLDVTAED IIVLKNIGPK GAPGMPEAGY IPIPMKLARA GVKDIVRISD
GRMSGTAFGT IVLHVTPESA IGGPLAQVRN GDRIRLSVKN REISLLISEA EMAKRIQENP
ITPPTAERGY KKLFLDTVTQ ADQGVDFDFL RAAKIVGKTP SK
//
