ID A4TCZ5_MYCGI Unreviewed; 575 AA.
AC A4TCZ5;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=GAF sensor signal transduction histidine kinase {ECO:0000313|EMBL:ABP46316.1};
GN OrderedLocusNames=Mflv_3844 {ECO:0000313|EMBL:ABP46316.1};
OS Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS PYR-GCK)).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350054 {ECO:0000313|EMBL:ABP46316.1};
RN [1] {ECO:0000313|EMBL:ABP46316.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PYR-GCK {ECO:0000313|EMBL:ABP46316.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP46316.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PYR-GCK {ECO:0000313|EMBL:ABP46316.1};
RX PubMed=23469141;
RA Badejo A.C., Badejo A.O., Shin K.H., Chai Y.G.;
RT "A Gene Expression Study of the Activities of Aromatic Ring-Cleavage
RT Dioxygenases in Mycobacterium gilvum PYR-GCK to Changes in Salinity and pH
RT during Pyrene Degradation.";
RL PLoS ONE 8:E58066-E58066(2013).
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DR EMBL; CP000656; ABP46316.1; -; Genomic_DNA.
DR AlphaFoldDB; A4TCZ5; -.
DR STRING; 350054.Mflv_3844; -.
DR KEGG; mgi:Mflv_3844; -.
DR eggNOG; COG3850; Bacteria.
DR HOGENOM; CLU_034370_1_0_11; -.
DR OrthoDB; 5241249at2; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF56; OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DOST; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABP46316.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 66..213
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 234..378
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 487..575
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 575 AA; 61360 MW; A61AC4649E1BE25E CRC64;
MHDGAVADAD DHRARDGARP VRTTLSQLRL RELLTEVQDR VEQIIRGRDR LDGLVEAMLA
VTSGLELDET LRTIVHTAIE LVDAQYGALG VRGHDQELVE FIYEGIDEPM RERIGHLPEG
RGVLGVLIND PKPIRLEDIS RHADSVGFPP NHPPMRTFLG VPVRIRDEVF GNLYLTEKSD
GQPFSEDDEV LVQALAAAAG IAIDNARLYA QSQARQSWIE ATRDIGTELL SGIDPAGVFR
RVADRAQKLS GAAATLVAVP DDPDLPVGEV AELTVAASAG ETIAAAHDPI PVAGTAIGDA
FVHRTPGMTD RADIGIGATV GPALLLPLRA PDAVPGVLIV LRSVGAQPFR SDELDMLAAF
ADQAAQAWQL ASTQHRLREL GILTDRDRIA RDLHDHVIQR LFAVGLSLQG SIARARSEEV
QQRLSANVDD LQSVIQEIRT AIFDLHGGSS AVTRLRQRLD AAVAAFPESG VRTSMQCAGP
LSVVDAGLAD HAEAVVREAV SNAVRHAEAS TVAVTVTVED DLAITVTDDG RGIAADVTGS
GLANLARRAQ DVGGSFSVRR GAQVGTTLTW RAPLP
//
