ID A4TE01_MYCGI Unreviewed; 603 AA.
AC A4TE01;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Diguanylate cyclase with PAS/PAC sensor {ECO:0000313|EMBL:ABP46720.1};
GN OrderedLocusNames=Mflv_4251 {ECO:0000313|EMBL:ABP46720.1};
OS Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS PYR-GCK)).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350054 {ECO:0000313|EMBL:ABP46720.1};
RN [1] {ECO:0000313|EMBL:ABP46720.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PYR-GCK {ECO:0000313|EMBL:ABP46720.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP46720.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PYR-GCK {ECO:0000313|EMBL:ABP46720.1};
RX PubMed=23469141;
RA Badejo A.C., Badejo A.O., Shin K.H., Chai Y.G.;
RT "A Gene Expression Study of the Activities of Aromatic Ring-Cleavage
RT Dioxygenases in Mycobacterium gilvum PYR-GCK to Changes in Salinity and pH
RT during Pyrene Degradation.";
RL PLoS ONE 8:E58066-E58066(2013).
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DR EMBL; CP000656; ABP46720.1; -; Genomic_DNA.
DR AlphaFoldDB; A4TE01; -.
DR STRING; 350054.Mflv_4251; -.
DR KEGG; mgi:Mflv_4251; -.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_11_32_11; -.
DR OrthoDB; 9151676at2; -.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
FT DOMAIN 269..326
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 327..398
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 483..603
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 65824 MW; 967D2993F60EC1DB CRC64;
MNVTGWCSLS GKIPGRGPSP GDAKDDEVAR LLALESFDIL DTPPEESFDG LTALAAYVCD
VPMALIGFLD AERQWLKSRQ GVGHSEIARE LSFCASTMGD GDTLIEIPDT RLDSRLAGHP
MVTGDPHLRF YAGMPIRTAE GHALGTICVM DVEPRTLSDA QRSHLRTLAD QVMNLLDLRR
RARQYAVEMT RRLEIDEALR QQQRLLSGVL DHTDVLVYTK DVEGRFVMAN NAVQHVTQAD
RSMIGATDYD FFDATVADSY RRNDRRIMET REWQVFSEDV VHPDGSVHTY RSTKFPLISD
SGEVLGVGGL STDVTELAAA RAAHEAAEER WRALVEQSPA PVIVVDAEGA LAYVNPEGLA
LLGVARGADV SLLPAEDFIP PQLRRATQKL LDETMAGTRV VRGERGVLRR RDGTEITVEI
NATVVSHSGE RSVQLEIRDV SEVAAAHAAL EHSASTDPLT GVLNRKAWDA RVATLLPEVS
DTSPMTIAVI DLDNFKTYND TRGHTAGDAL LQQFAGAAAA CLGADDVFAR WGGEEFIVAL
PGADPDRAEP ILDRLRGHVP SEQTCSIGYT GHVPPEALTD TVIRADKALY QAKRRGKNRI
ARL
//
