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Database: UniProt
Entry: A4VW86_STRSY
LinkDB: A4VW86_STRSY
Original site: A4VW86_STRSY 
ID   A4VW86_STRSY            Unreviewed;       714 AA.
AC   A4VW86;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   08-MAY-2019, entry version 79.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=SSU05_1409 {ECO:0000313|EMBL:ABP90375.1};
OS   Streptococcus suis (strain 05ZYH33).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=391295 {ECO:0000313|EMBL:ABP90375.1, ECO:0000313|Proteomes:UP000000243};
RN   [1] {ECO:0000313|EMBL:ABP90375.1, ECO:0000313|Proteomes:UP000000243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05ZYH33 {ECO:0000313|EMBL:ABP90375.1,
RC   ECO:0000313|Proteomes:UP000000243};
RX   PubMed=17375201; DOI=10.1371/journal.pone.0000315;
RG   BGI;
RA   Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F.,
RA   Pan X., Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z.,
RA   Ju A., Ge J., Dong Y., Sun W., Jiang Y., Wang J., Yan J., Yang H.,
RA   Wang X., Gao G.F., Yang R., Wang J., Yu J.;
RT   "A glimpse of streptococcal toxic shock syndrome from comparative
RT   genomics of S. suis 2 Chinese isolates.";
RL   PLoS ONE 2:E315-E315(2007).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP000407; ABP90375.1; -; Genomic_DNA.
DR   STRING; 391295.SSU05_1409; -.
DR   EnsemblBacteria; ABP90375; ABP90375; SSU05_1409.
DR   KEGG; ssu:SSU05_1409; -.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   HOGENOM; HOG000054021; -.
DR   KO; K04759; -.
DR   OMA; MEMPDYE; -.
DR   BioCyc; SSUI391295:GHI8-1461-MONOMER; -.
DR   Proteomes; UP000000243; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000243};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000243};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    280    298       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    343    367       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    452    472       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    511    532       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    544    562       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    569    589       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    609    631       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    643    670       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    676    694       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        2    163       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   714 AA;  79132 MW;  D4DC7664095296B8 CRC64;
     MTKHIALAGN PNSGKTTLFN LLTGTNQRVG NWPGVTVERK SGTIKKRKHL LIQDLPGIYS
     LSPYTPEERV ARDYLIADQP AAILNVLDAT NLERNLYLTL QLLEMGLPIV IALNMTDALK
     SQGRSINSDQ LSYQLGVPVQ PISALKKLGI SQLLHEVEKI TNQQAEPIYP QYDKQFEAGL
     AQVIDLLSDS IPNRQKRFYA IKLLEQDQVI LDQLQLNAQD MLDLTEIIAI LEKIYADDME
     AIIVNQRYQF IEKITELVTK DSDKAFNLSD NIDRLVTNRF LALPIFAAVM WLTYFLSIQT
     VGTMGTDWVN DVLFGELVPG LIQANLDRFE IAGWLQSLVL DGIIAGCGAI LGFVPQIFVL
     FVCLGILEDI GYMSRVAFVM DRIFRRFGLS GKSFIPMLIS TGCGVPGVMA SRTIENEQDR
     KITIMTATFM PCSAKLPIIS LVAGAFFPDN PWIAPSAYFV GMAAIVLSGM ALKKTKQLGG
     VASPFIMELP SYHLPKLSTV LRYAFDKALS FIKRAGTIIF VTNIIIWFSS SYNWSLQMVE
     TDESILASIG HSFSLLFAPL GFGNWRATVA AITGLLAKET VIATFGILYK LGETTEENPE
     LWGLLQQDYT ALSAYSFLVF NLLCAPCFAA IGAIHREMGE AKWTWIAIGF QTGLAYASSL
     VIYQIGLVLI HGQLPTVWTF IAIFLIITAI YSLVKKPTNT LPIVTLKTLE KGEY
//
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