ID A4WKN9_PYRAR Unreviewed; 312 AA.
AC A4WKN9;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=DNA repair and recombination protein RadA {ECO:0000256|PIRNR:PIRNR005856};
GN OrderedLocusNames=Pars_1396 {ECO:0000313|EMBL:ABP50956.1};
OS Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=340102 {ECO:0000313|EMBL:ABP50956.1, ECO:0000313|Proteomes:UP000001567};
RN [1] {ECO:0000313|EMBL:ABP50956.1, ECO:0000313|Proteomes:UP000001567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700994 / DSM 13514 / JCM 11321 / PZ6
RC {ECO:0000313|Proteomes:UP000001567};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Cozen A.E.,
RA Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.;
RT "Complete sequence of Pyrobaculum arsenaticum DSM 13514.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in DNA repair and in homologous recombination. Binds
CC and assemble on single-stranded DNA to form a nucleoprotein filament.
CC Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand
CC exchange between homologous DNA molecules.
CC {ECO:0000256|ARBA:ARBA00025684, ECO:0000256|PIRNR:PIRNR005856}.
CC -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family.
CC {ECO:0000256|PIRNR:PIRNR005856}.
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DR EMBL; CP000660; ABP50956.1; -; Genomic_DNA.
DR AlphaFoldDB; A4WKN9; -.
DR STRING; 340102.Pars_1396; -.
DR KEGG; pas:Pars_1396; -.
DR HOGENOM; CLU_041732_0_0_2; -.
DR OrthoDB; 31129at2157; -.
DR PhylomeDB; A4WKN9; -.
DR Proteomes; UP000001567; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR22942:SF39; DNA REPAIR PROTEIN RAD51 HOMOLOG 1; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|PIRNR:PIRNR005856};
KW DNA recombination {ECO:0000256|PIRNR:PIRNR005856};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR005856};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 80..248
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 312 AA; 34929 MW; CAABD0AD0F7CF083 CRC64;
MSRRKTERDD LSSLEGVGPK TLERLRELGV VSVEHLAEFT VEELVEAGVE YDRAVKIIQQ
ALAKAGGVRA ATVKELRARQ YKTFKTGVAD FDEKTPWRGI REGFIYEFAG EFGAGKSMLA
HQLSVAALKE GFTGRVVYID TEGTFSHELV EAVAKRFEAD IDKVGDSVYV YQPANVVQLE
QIVKFEIPKH VAEGCRLVVV DTITALYRAE FVGREHLAAR QQRIHYLVDW LRRHARTFGV
TSILTNQVMD VPEVFASKRP AGGNVIAHAV NARFMMSRPN KMRPEGRMWP LDVPGMAPDV
EIAYQISSDG LH
//
