ID A4X470_SALTO Unreviewed; 391 AA.
AC A4X470;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=ROK family protein {ECO:0000313|EMBL:ABP53670.1};
GN OrderedLocusNames=Strop_1200 {ECO:0000313|EMBL:ABP53670.1};
OS Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC
OS 105044 / CNB-440).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Salinispora.
OX NCBI_TaxID=369723 {ECO:0000313|EMBL:ABP53670.1, ECO:0000313|Proteomes:UP000000235};
RN [1] {ECO:0000313|Proteomes:UP000000235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC {ECO:0000313|Proteomes:UP000000235};
RX PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA Jensen P.R., Moore B.S.;
RT "Genome sequencing reveals complex secondary metabolome in the marine
RT actinomycete Salinispora tropica.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000667; ABP53670.1; -; Genomic_DNA.
DR RefSeq; WP_011905102.1; NC_009380.1.
DR AlphaFoldDB; A4X470; -.
DR STRING; 369723.Strop_1200; -.
DR KEGG; stp:Strop_1200; -.
DR PATRIC; fig|369723.5.peg.1223; -.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_3_11; -.
DR Proteomes; UP000000235; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000235}.
FT DOMAIN 20..70
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
SQ SEQUENCE 391 AA; 39996 MW; EEFCCBA7C788622F CRC64;
MTMTRLPGTP RLLRALNDRA ALELLLEQGP LTRARLGELT GLSKVTASQL VERLEERGLV
TRVGEQAGGR GPNAQLYAVR PGSAHVVGVD FGAERVVAAC ADITGAVVGR AEHPTGDTDD
PVGVVHHTVV QAASSAGAPL ATVRRVVLGA PGLVDPTSGD ITFAFNLPRW HAGLLGALRD
DLRAPVAFEN DVNLVAMAEA RSGAAQGVAD FVLVWVDAGI GLAIVFGGRL HHGSTGAAGE
IGWLPVPGVP IPHAAALRTK PAFQQLVGGE AVRALAREHG YPDDSVAGGV AAAIADGPAG
DPMLDELARR LALGVASTAV VLDPPLVVLA GAVGRAGGAA LAERVQREVA AIALVRPRVV
PTGLTEEPIL RGALHTALEA VRDEVFGSTT S
//
