ID   A4X5A8_SALTO            Unreviewed;       776 AA.
AC   A4X5A8;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN   OrderedLocusNames=Strop_1592 {ECO:0000313|EMBL:ABP54058.1};
OS   Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC
OS   105044 / CNB-440).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Salinispora.
OX   NCBI_TaxID=369723 {ECO:0000313|EMBL:ABP54058.1, ECO:0000313|Proteomes:UP000000235};
RN   [1] {ECO:0000313|Proteomes:UP000000235}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC   {ECO:0000313|Proteomes:UP000000235};
RX   PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA   Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA   Jensen P.R., Moore B.S.;
RT   "Genome sequencing reveals complex secondary metabolome in the marine
RT   actinomycete Salinispora tropica.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
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DR   EMBL; CP000667; ABP54058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4X5A8; -.
DR   STRING; 369723.Strop_1592; -.
DR   KEGG; stp:Strop_1592; -.
DR   eggNOG; COG3973; Bacteria.
DR   HOGENOM; CLU_010312_3_1_11; -.
DR   Proteomes; UP000000235; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13245; AAA_19; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000000235}.
FT   DOMAIN          202..627
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         223..230
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   776 AA;  84256 MW;  698E85B7D8083DCD CRC64;
     MRDGLSSNSG VVQHSGGPGD SPIHDDEIGQ EQEYVSMLYG RLDALREQAT HRLAEQLRAT
     GGTLQARSQR DSAVRMYGEQ VEQYSAVEQG LCFGRLDTDD GGRHYIGRIG IFDSDGDYDP
     LLIDWRAPAA RAFYLATAAN PQGVHRRRHL RTRQRKVTGL NDEVLDIAAA SPTAHEELTG
     EAALLAALTA GRTGRMRDIV ETIQAEQDTV IRAELPGTLV VQGGPGTGKT AVALHRAAYL
     LYTHRRELAT RGVLLVGPNA TFLRYISQVL PALAETGVLL RTQADLFPGV TARRTEGAEA
     AALKGRAVLV EVLAAAVRDR QWVPDEPLEI EQPQREILVL HPETVRAARD RARRSGRPHN
     LARAVFDVEL VHALAAQVAE RIGADPLGGE NLLEEADLAE IRRELRDDPE VRATLDHLWP
     LLTPQQLLAD LYADPARIAT AAPMLTEAEQ ALLHRQPSGW TPADVPLLDE AAELLGEDDR
     AAAARRERLR TLQREYAEGV LEIARGSRSI DVEDEADGGE ILGVTDLLDA DRMVERQEEG
     DRLTTAQRAA ADRSWAFGHI IVDEAQELSP MAWRLLMRRC PSRSMTIVGD VAQTGALAGT
     ASWAEVLEPY VARRWRLTEL AVSYRTPAEI MAVAAEVLAQ IDPTLRPPRS VRSTGVPPID
     RSVAPERLAA ELVDAATATA ATLTDGRLGV IVPAARVADL GPALADAIPE ATVGDQPDLK
     GRTVLLTVAQ AKGLEFDAVL VVDPDGIVAE SPRGRNDLYV ALTRATQRLT VLRPTS
//