ID A4XFJ4_CALS8 Unreviewed; 899 AA.
AC A4XFJ4;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Type III restriction enzyme, res subunit {ECO:0000313|EMBL:ABP65679.1};
GN OrderedLocusNames=Csac_0015 {ECO:0000313|EMBL:ABP65679.1};
OS Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T
OS 6331).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=351627 {ECO:0000313|EMBL:ABP65679.1, ECO:0000313|Proteomes:UP000000256};
RN [1] {ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A.,
RA VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J.,
RA Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M.,
RA Kengen S.M.W., Richardson P.;
RT "Genome sequence of the thermophilic hydrogen-producing bacterium
RT Caldicellulosiruptor saccharolyticus DSM 8903.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP65679.1, ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RX PubMed=18776029; DOI=10.1128/AEM.00968-08;
RA van de Werken H.J., Verhaart M.R., VanFossen A.L., Willquist K.,
RA Lewis D.L., Nichols J.D., Goorissen H.P., Mongodin E.F., Nelson K.E.,
RA van Niel E.W., Stams A.J., Ward D.E., de Vos W.M., van der Oost J.,
RA Kelly R.M., Kengen S.W.;
RT "Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor
RT saccharolyticus.";
RL Appl. Environ. Microbiol. 74:6720-6729(2008).
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DR EMBL; CP000679; ABP65679.1; -; Genomic_DNA.
DR RefSeq; WP_011915646.1; NC_009437.1.
DR AlphaFoldDB; A4XFJ4; -.
DR STRING; 351627.Csac_0015; -.
DR KEGG; csc:Csac_0015; -.
DR eggNOG; COG1061; Bacteria.
DR eggNOG; COG3886; Bacteria.
DR HOGENOM; CLU_005588_2_0_9; -.
DR OrthoDB; 9802848at2; -.
DR Proteomes; UP000000256; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd09205; PLDc_N_DEXD_b3; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50035; PLD; 1.
PE 4: Predicted;
FT DOMAIN 132..163
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 301..451
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 505..659
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 899 AA; 105571 MW; 804E83E95509A89F CRC64;
MNSERLKAIQ EHLTKISIED VAEIYKDLEN IYNQLLSKHG IDIQKCFCGA NENFLEELKK
AFSKAVEINM IVSFLLESGV RLIIEDLIEA KKRNCPIRIV TGRYLNITQP SALYLIKDRL
GSYVDLRFFK DDNIPFHPKA YIIEYEGGKG DIFIGSSNLS ESALTYGIEW NYRIEKTTNP
KDYEQFKKEF FKILKSCTEK IDDELLRKYS RSWKRPKIFI EIKEIQAEVE NTDNSAEDID
STSSKDISMV AEEVLEYDKS TFAEKDDTEQ SKTQHKKPNS RKIVPLYPRE AQTEALYWLK
KCREEGLDRA LVVAATGIGK TFLAAFDSIG FKTVLFVAHR EEILRQAALS FKTIRSNATI
GFFTGDRKET EKDIIFASVQ TLGKEEYLNP TYFSSDYFEY IIIDEFHHAV AKSYQNIINY
FKPKFLLGLT ATPERLDNKD VFELCNYNVV YELRLKDAIN KGYLVPFHYY GIYDETDFSQ
IPEINGKYKE DELEKVLMIH KRADLILKNY LKFNKQKTLA FCCSRNHAEF MADYFNKNGV
KCCAVYSGEQ GKNALQRSEA IRKLKNGQIK VIFTVDMFNE GVDIPEIDMV MFLRPTESPT
VFLQQLGRGL RKAKNKNYLT VLDFIGNYKR ANLIPFLLST GEYDIEKIQK SKYSVDDFEY
PDGCVVDFDF RIIDIFKKQA ESLKNIQEIV YEEFLRIKEM LGKRPSRVEF FKYIDTAIYA
SMKKYSDPFI NVFKDYISFL KINNQLEEGE ESLFNTFAHK FIKVVENTMM TKIYKMPLLL
AFYNNGNIKL KVGPDDIYEA FKEFFSNPSN AIDLEVHKST RNYKDWQKEE YIKLSRNNPE
KYLISSHPEF FYWDGDYFCI NDKLADFINN EYFLVHFKDA IDFRIKRYYR ERYEKWTQQ
//
