ID A4XJQ3_CALS8 Unreviewed; 332 AA.
AC A4XJQ3;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 2.
DT 24-JAN-2024, entry version 75.
DE SubName: Full=Hydrogenase expression/formation protein HypE {ECO:0000313|EMBL:ABP67138.2};
GN OrderedLocusNames=Csac_1545 {ECO:0000313|EMBL:ABP67138.2};
OS Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T
OS 6331).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=351627 {ECO:0000313|EMBL:ABP67138.2, ECO:0000313|Proteomes:UP000000256};
RN [1] {ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A.,
RA VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J.,
RA Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M.,
RA Kengen S.M.W., Richardson P.;
RT "Genome sequence of the thermophilic hydrogen-producing bacterium
RT Caldicellulosiruptor saccharolyticus DSM 8903.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP67138.2, ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RX PubMed=18776029; DOI=10.1128/AEM.00968-08;
RA van de Werken H.J., Verhaart M.R., VanFossen A.L., Willquist K.,
RA Lewis D.L., Nichols J.D., Goorissen H.P., Mongodin E.F., Nelson K.E.,
RA van Niel E.W., Stams A.J., Ward D.E., de Vos W.M., van der Oost J.,
RA Kelly R.M., Kengen S.W.;
RT "Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor
RT saccharolyticus.";
RL Appl. Environ. Microbiol. 74:6720-6729(2008).
CC -!- SIMILARITY: Belongs to the HypE family.
CC {ECO:0000256|ARBA:ARBA00006243}.
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DR EMBL; CP000679; ABP67138.2; -; Genomic_DNA.
DR RefSeq; WP_011917073.1; NC_009437.1.
DR AlphaFoldDB; A4XJQ3; -.
DR STRING; 351627.Csac_1545; -.
DR KEGG; csc:Csac_1545; -.
DR eggNOG; COG0309; Bacteria.
DR HOGENOM; CLU_049733_0_0_9; -.
DR OrthoDB; 9801934at2; -.
DR Proteomes; UP000000256; Chromosome.
DR CDD; cd02197; HypE; 1.
DR Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR InterPro; IPR011854; HypE.
DR InterPro; IPR010918; PurM-like_C_dom.
DR InterPro; IPR036676; PurM-like_C_sf.
DR InterPro; IPR016188; PurM-like_N.
DR InterPro; IPR036921; PurM-like_N_sf.
DR NCBIfam; TIGR02124; hypE; 1.
DR PANTHER; PTHR30303:SF0; CARBAMOYL DEHYDRATASE HYPE; 1.
DR PANTHER; PTHR30303; HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPE; 1.
DR Pfam; PF00586; AIRS; 1.
DR Pfam; PF02769; AIRS_C; 1.
DR PIRSF; PIRSF005644; Hdrgns_mtr_HypE; 1.
DR SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 35..147
FT /note="PurM-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00586"
FT DOMAIN 163..310
FT /note="PurM-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02769"
SQ SEQUENCE 332 AA; 37046 MW; 4EB5CD943AA9316B CRC64;
MKFIQKEHGN GGKQTYELIN ELFKPIFDSE ILKRGDDSSI FDLASKKIGV TTDSFVVKPY
FFKGGDIGKL SVCGTVNDLA VSGLVPKYIT ASFIIEEGFP IVDLQKIVKS MKEYADIAGV
EIVAGDTKVV EKGSCDGIFI NTTGFGVCEK EEKFPSIEKI KGGQVILVSG DIGRHGACIY
SHNSEFGFEE KIESDCAPLN RVINELLENV EICYMKDLTR GGLATALNEI AQKANVAIYV
EEDKVPVSNE VKALCDILGL DWYYLACEGR FVAIVNRKNE QRALEILRKY NKEACEIGWI
EDTEENRVYL RTSFGGTRIL DMLYYDMLPR IC
//
