ID A4XRE4_PSEMY Unreviewed; 284 AA.
AC A4XRE4;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=Pmen_1143 {ECO:0000313|EMBL:ABP83910.1};
OS Pseudomonas mendocina (strain ymp).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=399739 {ECO:0000313|EMBL:ABP83910.1};
RN [1] {ECO:0000313|EMBL:ABP83910.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ymp {ECO:0000313|EMBL:ABP83910.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Hersman L., Dubois J., Maurice P., Richardson P.;
RT "Complete sequence of Pseudomonas mendocina ymp.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000680; ABP83910.1; -; Genomic_DNA.
DR AlphaFoldDB; A4XRE4; -.
DR STRING; 399739.Pmen_1143; -.
DR KEGG; pmy:Pmen_1143; -.
DR PATRIC; fig|399739.8.peg.1158; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_0_0_6; -.
DR OrthoDB; 9792284at2; -.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..284
FT /note="D-lactate dehydratase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002675814"
FT DOMAIN 50..177
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 284 AA; 30442 MW; 85331E577A5D8C78 CRC64;
MSKKTTLAVA VAGSLLAGSA LAAGKGEVLV LLSSETQLPL KDGKQYTTGF YLNEFGVPAD
HLLKAGYELV LVTPKGNAPR VDENSVTPQY FGGDEQEMQR IRSLVENLPG IDDTLSLKEV
LEGDLQRYAG LLIPGGHAPL IDLANNPEVG ALLRHFHQAG KPTAAICHGP IALLSAQRDP
AAYQAALANG ETPAAADWIY QGYRMTIFST PEEQVFEQSL QGERILFYPA TAMESAGGEL
SYTEAWAPNV VVDRELITGQ NPFSDHALGK KLVQMLDAKG QQAQ
//
