ID   A4XS61_PSEMY            Unreviewed;       214 AA.
AC   A4XS61;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE            EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE   AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN   OrderedLocusNames=Pmen_1412 {ECO:0000313|EMBL:ABP84177.1};
OS   Pseudomonas mendocina (strain ymp).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=399739 {ECO:0000313|EMBL:ABP84177.1};
RN   [1] {ECO:0000313|EMBL:ABP84177.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ymp {ECO:0000313|EMBL:ABP84177.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Hersman L., Dubois J., Maurice P., Richardson P.;
RT   "Complete sequence of Pseudomonas mendocina ymp.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC       from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC   -!- SIMILARITY: Belongs to the isochorismatase family.
CC       {ECO:0000256|ARBA:ARBA00006336}.
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DR   EMBL; CP000680; ABP84177.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4XS61; -.
DR   STRING; 399739.Pmen_1412; -.
DR   KEGG; pmy:Pmen_1412; -.
DR   PATRIC; fig|399739.8.peg.1433; -.
DR   eggNOG; COG1335; Bacteria.
DR   HOGENOM; CLU_068979_13_1_6; -.
DR   OrthoDB; 9791276at2; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd01011; nicotinamidase; 1.
DR   Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR   InterPro; IPR000868; Isochorismatase-like.
DR   InterPro; IPR036380; Isochorismatase-like_sf.
DR   PANTHER; PTHR11080:SF2; LD05707P; 1.
DR   PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR   Pfam; PF00857; Isochorismatase; 1.
DR   SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ABP84177.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642}.
FT   DOMAIN          7..199
FT                   /note="Isochorismatase-like"
FT                   /evidence="ECO:0000259|Pfam:PF00857"
SQ   SEQUENCE   214 AA;  22996 MW;  0C20F83C068E40D8 CRC64;
     MKIASFDVDA QKGFTPLCPG ELPVPEGDAI VPALNQLATR AQLRIGSKDA HSPQAAWVVD
     SHAQMLQPLP LANADLTWVS HCVPGTPGFE LLEGLPAPLD YDYFVWKGVE PDMHPYGACY
     HDLAEKRSTG VIEFLRHNAV DHILVGGLAL DYCVKTTALQ LRRAGFAVTV YLPACRAIAR
     DTADAACTAM REQGITLASS LDELDSALAT ETQG
//