ID A4YEB9_METS5 Unreviewed; 452 AA.
AC A4YEB9;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN OrderedLocusNames=Msed_0596 {ECO:0000313|EMBL:ABP94771.1};
OS Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS / TH2).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP94771.1, ECO:0000313|Proteomes:UP000000242};
RN [1] {ECO:0000313|EMBL:ABP94771.1, ECO:0000313|Proteomes:UP000000242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC {ECO:0000313|Proteomes:UP000000242};
RX PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT archaeon Metallosphaera sedula provides insights into bioleaching-
RT associated metabolism.";
RL Appl. Environ. Microbiol. 74:682-692(2008).
CC -!- SIMILARITY: Belongs to the RuvB family.
CC {ECO:0000256|ARBA:ARBA00007519}.
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DR EMBL; CP000682; ABP94771.1; -; Genomic_DNA.
DR AlphaFoldDB; A4YEB9; -.
DR STRING; 399549.Msed_0596; -.
DR KEGG; mse:Msed_0596; -.
DR eggNOG; arCOG04081; Archaea.
DR HOGENOM; CLU_028311_1_1_2; -.
DR Proteomes; UP000000242; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.50.360; RuvB-like helicase, domain II; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR027238; RuvB-like.
DR InterPro; IPR041048; RuvB-like_C.
DR InterPro; IPR042487; RuvBL1/2_DNA/RNA_bd_dom.
DR InterPro; IPR010339; TIP49_P-loop.
DR PANTHER; PTHR11093:SF6; RUVB-LIKE 1; 1.
DR PANTHER; PTHR11093; RUVB-RELATED REPTIN AND PONTIN; 1.
DR Pfam; PF06068; TIP49; 1.
DR Pfam; PF17856; TIP49_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000242}.
FT DOMAIN 62..384
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 452 AA; 50013 MW; B148F0F698DA018D CRC64;
MAEIKEVRKV ETGRASIHSH ITGLGVDENG KAKFKADGLV GQLEAREAAW VVVQLIKQGK
MAGKGILLVG PPGTGKTALA VGIAKELGED TPFNTLNASE IYSVDLKKTE VLTQALRKSI
GVRVRQRRMV YEGVVKDVKM RIARSRINPY VQIPREVELK LATKDEERTL TAGETIAEQI
SKMGIRKGDV IWIDAETGNV VKVGKAKDVE GAKTFDIDTA RTVEIPSGPV KKEKELTNTF
TLYDLDLTLA AQSISITALF SLWSEREVSQ DIRKQVDAYV KDMINKGTAE LIPGVLFIDD
AHMLDIETFS FLTKALEAEL APILVLATNR GTTKIRGTDV EAPHGMPLDL LDRLLIITTR
PYSKEESREI ISIRAEELDI ELEPAALDEL TSMAAEESLR YSIQLLEPSQ VIARKAGRGI
VKAEDVKEAS RLFSDLKRSV KYVKEYENLF LK
//
