ID A5AB73_ASPNC Unreviewed; 358 AA.
AC A5AB73;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Contig An08c0230, genomic contig {ECO:0000313|EMBL:CAK96707.1};
DE EC=4.1.1.- {ECO:0000313|EMBL:CAK96707.1};
GN ORFNames=An08g09280 {ECO:0000313|EMBL:CAK96707.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK96707.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK96707.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR EMBL; AM270178; CAK96707.1; -; Genomic_DNA.
DR RefSeq; XP_001393039.2; XM_001393002.2.
DR AlphaFoldDB; A5AB73; -.
DR EnsemblFungi; CAK96707; CAK96707; An08g09280.
DR GeneID; 4983246; -.
DR VEuPathDB; FungiDB:An08g09280; -.
DR HOGENOM; CLU_028458_2_1_1; -.
DR Proteomes; UP000006706; Chromosome 8R.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF86; FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G07000); 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:CAK96707.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT DOMAIN 64..259
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 358 AA; 39622 MW; 1AB7B5344068A5C8 CRC64;
MATFKQLVRF AVGDQTHYGE LINTDGNKYT VQQFDGTPFD KLLLTDKTYT VTDLLPPVPN
TPLVICIGLN YKQHAKEASL DVPTYPPVFT KPADVLAGPF ETIPIHRDAQ SHLDYEGELT
VVIGKDAKNV SAEDALDYVL GYTAGNDLSA RNFQMPEASG GQFCYAKSFD KFAPIGHVLV
SAQEVQDPQQ LSLVTKVNGV VKQTTNTSDM IWGVRDIVSH LSRGMTLRKG TLIMTGTPSG
VGFFRKEFLQ DGDVVEVELG VREPGVIDFI LFYFSRQAFP SWLHPESRHM CIRLVFRGAL
VGKELRYSVM VGKASVLGQH PNGMGRQWSR IAYRFLPADR QYMDAGTKSS TTNLGTDS
//
