ID A5ADC4_VITVI Unreviewed; 728 AA.
AC A5ADC4;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN OrderedLocusNames=VIT_07s0005g01770 {ECO:0000313|EMBL:CCB60032.1};
GN ORFNames=VITISV_036050 {ECO:0000313|EMBL:CAN64445.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CAN64445.1};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
RN [2] {ECO:0000313|EMBL:CAN64445.1}
RP NUCLEOTIDE SEQUENCE.
RA Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis
RT vinifera L.): coping with a highly heterozygous genome.";
RL PLoS ONE 2:e1326-e1326(2007).
RN [3] {ECO:0000313|EMBL:CCB60032.1}
RP NUCLEOTIDE SEQUENCE.
RA Vitulo N., Olivier J., Forcato C., Albiero A., D'Angelo M., Zimbello R.,
RA Schiavon R., Rigobello C., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Vezzi A., Hugueney P., Horner D., Mica E., Cattonaro F.,
RA Del Fabbro C., Alaux M., Di Gaspero G., Scalabrin S., Pesole G.,
RA Delledonne M., Pezzotti M., Pe E.M., Caboche M., Adam-Blondon A.-F.,
RA Weissenbach J., Quetier F., Wincker P., Morgante M., Valle G.;
RT "High quality assembly and annotation of grapevine genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM423680; CAN64445.1; -; Genomic_DNA.
DR EMBL; FN596502; CCB60032.1; -; Genomic_DNA.
DR RefSeq; XP_002278247.1; XM_002278211.4.
DR AlphaFoldDB; A5ADC4; -.
DR STRING; 29760.A5ADC4; -.
DR PaxDb; 29760-VIT_07s0005g01770-t01; -.
DR EnsemblPlants; Vitvi07g00442_t001; Vitvi07g00442_P001; Vitvi07g00442.
DR GeneID; 100253689; -.
DR Gramene; Vitvi07g00442_t001; Vitvi07g00442_P001; Vitvi07g00442.
DR KEGG; vvi:100253689; -.
DR eggNOG; KOG0925; Eukaryota.
DR HOGENOM; CLU_001832_5_11_1; -.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000009183; Chromosome 7.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17973; DEXHc_DHX15; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR044756; DHX15_DEXHc.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF109; ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183}.
FT DOMAIN 74..243
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 268..448
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 728 AA; 82698 MW; DBE94473FB178841 CRC64;
MGTERKRKVS LFDVVDETSV SAKISKSNGS GAINNNNNNN LVNRWNGRPY SQRYYEILEK
RRTLPVWHQK EEFLQVLKAN QSLILVGETG SGKTTQIPQF VLEAVDIETP DKRKKMMIAC
TQPRRVAAMS VSRRVAEEMD VTIGEEVGYS IRFEDCSSAR TVLKYLTDGM LLREAMTDPL
LERYKVIILD EAHERTLATD VLFGLLKEVL KNRPDLKVVV MSATLEAEKF QGYFNGAPLM
KVPGRLHPVE IFYTQEPERD YLEAAIRTVV QIHMCEGAGD ILVFLTGEEE IEDACKKISK
EIANLGDQVG PVKAVPLYST LPPAMQQKIF EPAPPPLTEG GPPGRKIVVS TNIAETSLTI
DGIVFVIDPG FAKQKVYNPR VRVESLLVSP ISKASAHQRS GRAGRTQPGK CFRLYTEKSF
NNDLQPQTYP EILRSNLANT VLTLKKLGID DLVHFDFMDP PAPETLMRAL EVLNYLGALD
DDGNLTKLGE IMSEFPLDPQ MSKMLVVSPE FNCSNEILSI SAMLSVPNCF VRPREAQKAA
DEAKARFGHI DGDHLTLLNV YHAYKQNNED PSWCYENFVN QRALKAADNV RQQLVRIMAR
FNLKLCSTDF NSRDYYINIR KAMLAGYFMQ VAHLERTGHY LTVKDNQVVH LHPSNCLDHK
PEWVIYNEYV LTSRNFIRTV TDVRGEWLVD VAPHYYDLAN FPNCEAKRVL EKLYKKREKD
REESRNRK
//
