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Database: UniProt
Entry: A5CEI5_ORITB
LinkDB: A5CEI5_ORITB
Original site: A5CEI5_ORITB 
ID   A5CEI5_ORITB            Unreviewed;       213 AA.
AC   A5CEI5;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   16-JAN-2019, entry version 68.
DE   RecName: Full=Superoxide dismutase {ECO:0000256|RuleBase:RU000414};
DE            EC=1.15.1.1 {ECO:0000256|RuleBase:RU000414};
GN   Name=sodB {ECO:0000313|EMBL:CAM80570.1};
GN   OrderedLocusNames=OTBS_1489 {ECO:0000313|EMBL:CAM80570.1};
OS   Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Orientia.
OX   NCBI_TaxID=357244 {ECO:0000313|EMBL:CAM80570.1, ECO:0000313|Proteomes:UP000001565};
RN   [1] {ECO:0000313|EMBL:CAM80570.1, ECO:0000313|Proteomes:UP000001565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Boryong {ECO:0000313|EMBL:CAM80570.1,
RC   ECO:0000313|Proteomes:UP000001565};
RX   PubMed=17483455; DOI=10.1073/pnas.0611553104;
RA   Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y.,
RA   Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J.,
RA   Koh Y.-S., Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S.,
RA   Kim I.-S.;
RT   "The Orientia tsutsugamushi genome reveals massive proliferation of
RT   conjugative type IV secretion system and host-cell interaction
RT   genes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007).
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000414}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC         Evidence={ECO:0000256|RuleBase:RU000414};
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000256|RuleBase:RU000414}.
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DR   EMBL; AM494475; CAM80570.1; -; Genomic_DNA.
DR   RefSeq; WP_011944910.1; NC_009488.1.
DR   ProteinModelPortal; A5CEI5; -.
DR   STRING; 357244.OTBS_1489; -.
DR   EnsemblBacteria; CAM80570; CAM80570; OTBS_1489.
DR   GeneID; 29642989; -.
DR   KEGG; ots:OTBS_1489; -.
DR   eggNOG; ENOG4105CK4; Bacteria.
DR   eggNOG; COG0605; LUCA.
DR   HOGENOM; HOG000013584; -.
DR   KO; K04564; -.
DR   OMA; KWGSFDK; -.
DR   BioCyc; OTSU357244:G1GJM-1532-MONOMER; -.
DR   Proteomes; UP000001565; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001565};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000349-1,
KW   ECO:0000256|RuleBase:RU000414};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000414,
KW   ECO:0000313|EMBL:CAM80570.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001565}.
FT   DOMAIN       14     98       Sod_Fe_N. {ECO:0000259|Pfam:PF00081}.
FT   DOMAIN      106    206       Sod_Fe_C. {ECO:0000259|Pfam:PF02777}.
FT   COILED       43     63       {ECO:0000256|SAM:Coils}.
FT   METAL        38     38       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL        91     91       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL       173    173       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL       177    177       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
SQ   SEQUENCE   213 AA;  25039 MW;  61AD1BD4954FBCFA CRC64;
     MTFSKTANQT SYPFKLMELP YSKNSMEQYI SSEAFDYHHG KHHAAYVNNL NRLLEHKAEL
     QQKSLEDIIL TSFNSEGSKA IFNNAAQIWN HNFFWHSICN NNATKPEGNF LQKINQDFGS
     YENFTNQFQE LALAQFGSGW VWLISENCKL KIITTSNAEL PIIYNQIPLL TCDVWEHSYY
     IDYRNNRAKY LQQFIEHLAN WQFAEQNFLN SIK
//
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