ID A5CEI5_ORITB Unreviewed; 213 AA.
AC A5CEI5;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 16-JAN-2019, entry version 68.
DE RecName: Full=Superoxide dismutase {ECO:0000256|RuleBase:RU000414};
DE EC=1.15.1.1 {ECO:0000256|RuleBase:RU000414};
GN Name=sodB {ECO:0000313|EMBL:CAM80570.1};
GN OrderedLocusNames=OTBS_1489 {ECO:0000313|EMBL:CAM80570.1};
OS Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Orientia.
OX NCBI_TaxID=357244 {ECO:0000313|EMBL:CAM80570.1, ECO:0000313|Proteomes:UP000001565};
RN [1] {ECO:0000313|EMBL:CAM80570.1, ECO:0000313|Proteomes:UP000001565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Boryong {ECO:0000313|EMBL:CAM80570.1,
RC ECO:0000313|Proteomes:UP000001565};
RX PubMed=17483455; DOI=10.1073/pnas.0611553104;
RA Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y.,
RA Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J.,
RA Koh Y.-S., Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S.,
RA Kim I.-S.;
RT "The Orientia tsutsugamushi genome reveals massive proliferation of
RT conjugative type IV secretion system and host-cell interaction
RT genes.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007).
CC -!- FUNCTION: Destroys radicals which are normally produced within the
CC cells and which are toxic to biological systems.
CC {ECO:0000256|RuleBase:RU000414}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC ChEBI:CHEBI:18421; EC=1.15.1.1;
CC Evidence={ECO:0000256|RuleBase:RU000414};
CC -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC family. {ECO:0000256|RuleBase:RU000414}.
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DR EMBL; AM494475; CAM80570.1; -; Genomic_DNA.
DR RefSeq; WP_011944910.1; NC_009488.1.
DR ProteinModelPortal; A5CEI5; -.
DR STRING; 357244.OTBS_1489; -.
DR EnsemblBacteria; CAM80570; CAM80570; OTBS_1489.
DR GeneID; 29642989; -.
DR KEGG; ots:OTBS_1489; -.
DR eggNOG; ENOG4105CK4; Bacteria.
DR eggNOG; COG0605; LUCA.
DR HOGENOM; HOG000013584; -.
DR KO; K04564; -.
DR OMA; KWGSFDK; -.
DR BioCyc; OTSU357244:G1GJM-1532-MONOMER; -.
DR Proteomes; UP000001565; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.287.990; -; 1.
DR Gene3D; 2.40.500.20; -; 1.
DR InterPro; IPR001189; Mn/Fe_SOD.
DR InterPro; IPR019833; Mn/Fe_SOD_BS.
DR InterPro; IPR019832; Mn/Fe_SOD_C.
DR InterPro; IPR019831; Mn/Fe_SOD_N.
DR InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR InterPro; IPR036314; SOD_C_sf.
DR Pfam; PF02777; Sod_Fe_C; 1.
DR Pfam; PF00081; Sod_Fe_N; 1.
DR PIRSF; PIRSF000349; SODismutase; 1.
DR PRINTS; PR01703; MNSODISMTASE.
DR SUPFAM; SSF46609; SSF46609; 1.
DR SUPFAM; SSF54719; SSF54719; 1.
DR PROSITE; PS00088; SOD_MN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000001565};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR000349-1,
KW ECO:0000256|RuleBase:RU000414};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000414,
KW ECO:0000313|EMBL:CAM80570.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001565}.
FT DOMAIN 14 98 Sod_Fe_N. {ECO:0000259|Pfam:PF00081}.
FT DOMAIN 106 206 Sod_Fe_C. {ECO:0000259|Pfam:PF02777}.
FT COILED 43 63 {ECO:0000256|SAM:Coils}.
FT METAL 38 38 Divalent metal cation.
FT {ECO:0000256|PIRSR:PIRSR000349-1}.
FT METAL 91 91 Divalent metal cation.
FT {ECO:0000256|PIRSR:PIRSR000349-1}.
FT METAL 173 173 Divalent metal cation.
FT {ECO:0000256|PIRSR:PIRSR000349-1}.
FT METAL 177 177 Divalent metal cation.
FT {ECO:0000256|PIRSR:PIRSR000349-1}.
SQ SEQUENCE 213 AA; 25039 MW; 61AD1BD4954FBCFA CRC64;
MTFSKTANQT SYPFKLMELP YSKNSMEQYI SSEAFDYHHG KHHAAYVNNL NRLLEHKAEL
QQKSLEDIIL TSFNSEGSKA IFNNAAQIWN HNFFWHSICN NNATKPEGNF LQKINQDFGS
YENFTNQFQE LALAQFGSGW VWLISENCKL KIITTSNAEL PIIYNQIPLL TCDVWEHSYY
IDYRNNRAKY LQQFIEHLAN WQFAEQNFLN SIK
//
