ID A5CYI4_PELTS Unreviewed; 402 AA.
AC A5CYI4;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Hypothetical membrane protein {ECO:0000313|EMBL:BAF60967.1};
GN OrderedLocusNames=PTH_2786 {ECO:0000313|EMBL:BAF60967.1};
OS Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Pelotomaculum.
OX NCBI_TaxID=370438 {ECO:0000313|EMBL:BAF60967.1, ECO:0000313|Proteomes:UP000006556};
RN [1] {ECO:0000313|Proteomes:UP000006556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13744 / JCM 10971 / SI {ECO:0000313|Proteomes:UP000006556};
RX PubMed=18218977; DOI=10.1101/gr.7136508;
RA Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.;
RT "The genome of Pelotomaculum thermopropionicum reveals niche-associated
RT evolution in anaerobic microbiota.";
RL Genome Res. 18:442-448(2008).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AP009389; BAF60967.1; -; Genomic_DNA.
DR AlphaFoldDB; A5CYI4; -.
DR STRING; 370438.PTH_2786; -.
DR KEGG; pth:PTH_2786; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_4_9; -.
DR Proteomes; UP000006556; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006556}.
FT DOMAIN 66..318
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 319..383
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 125..216
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 402 AA; 43079 MW; 1ACA04F176058AB1 CRC64;
MGKWLRISVA GLLVLSIALM AGCSIFKTAR LKNEEQDAVA VDKAMARHGK LTGGTVVTGK
LEALHSANVV PKMAGKVASI TVEVGSQVAE GDLLVSLDAA ELAALVDLYA AQLDKARNSD
LPAQKTQAEL ALANAEAAYK TARADYERSK QLREAGVISQ QQFEQAEKMY TQAEAAFKAA
QESLDILVNA TIPQTIRQFE AQLRKAQADY ANSIIRAPVG GVVTARNVNP GEMASPGQPV
VTIVALDPLV VQADVTEDQI NYIKVGQELK VRVSSVRDEP FTGIVTNISL AANPSTKAYP
VKIQISNPEH VLKPGMFAEV FLNTKEEEGI IVPREAVFKA EDKNFVWVIG DGRVMRREVA
VGQSDGRNVI ISSGLAEGEE VAVTGIDDLE DGTKVVVHNL IE
//
