ID   A5D3C5_PELTS            Unreviewed;       540 AA.
AC   A5D3C5;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Uncharacterized vancomycin resistance protein {ECO:0000313|EMBL:BAF59248.1};
GN   OrderedLocusNames=PTH_1067 {ECO:0000313|EMBL:BAF59248.1};
OS   Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC   Pelotomaculum.
OX   NCBI_TaxID=370438 {ECO:0000313|EMBL:BAF59248.1, ECO:0000313|Proteomes:UP000006556};
RN   [1] {ECO:0000313|Proteomes:UP000006556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13744 / JCM 10971 / SI {ECO:0000313|Proteomes:UP000006556};
RX   PubMed=18218977; DOI=10.1101/gr.7136508;
RA   Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.;
RT   "The genome of Pelotomaculum thermopropionicum reveals niche-associated
RT   evolution in anaerobic microbiota.";
RL   Genome Res. 18:442-448(2008).
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DR   EMBL; AP009389; BAF59248.1; -; Genomic_DNA.
DR   AlphaFoldDB; A5D3C5; -.
DR   STRING; 370438.PTH_1067; -.
DR   KEGG; pth:PTH_1067; -.
DR   eggNOG; COG2720; Bacteria.
DR   HOGENOM; CLU_011572_2_1_9; -.
DR   Proteomes; UP000006556; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR   InterPro; IPR011098; G5_dom.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF07501; G5; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
DR   SMART; SM01208; G5; 1.
DR   PROSITE; PS51109; G5; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006556};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          371..450
FT                   /note="G5"
FT                   /evidence="ECO:0000259|PROSITE:PS51109"
FT   REGION          456..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..480
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  57843 MW;  56AC526454D70876 CRC64;
     MLPVKITRII YGLLIAAAVV IPLVLFSSGF FAAVSKRVLP GIEVMGISLE GLNKAEGLAR
     LAELEKELRA TRVLLRYQED SWPLLLNEVG FNLNEEEIME AALSAGRSGP LLQRWQERKR
     FKKTGLSLKP VIEFDREKLA GRVNELAAKI IVKPRDASFQ INSDDTVTII PGSNGIGVDL
     GKLEEDIINV LSEGKKREVN LSLTTVPPAR STELLESMGV KGLLASYTTS FDPSKTSRTY
     NISVAAKAFD ELLIRPGHEV SFNKVVGPRS SEAGYKTAPI IVNNEFVDGL GGGVCQVSTT
     LYNCVLLANL DIIERSNHSI PVSYVPIGRD ATVVYDAIDF KFRNNTGDYL YVKSYVSNGH
     ITFKMYGNTA YKRDVSVNTW IVKEIEPKTV YETDPNLPKG EQVVKQEGSK GFIVAAERVV
     RKNGVVEKRE MLPSSDYSPV NKIIAVGVME RAVPQIAPST PAPSPVRLNE QVSGSQGNAA
     VTGPAGPGGS DGDQAPASGS GSPAVMVIPG SKPPAGGGDA GGSRAPGGWS APPERNGASP
//