ID A5D4I9_PELTS Unreviewed; 530 AA.
AC A5D4I9;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Iron only hydrogenase large subunit, C-terminal domain {ECO:0000313|EMBL:BAF58849.1};
GN OrderedLocusNames=PTH_0668 {ECO:0000313|EMBL:BAF58849.1};
OS Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Pelotomaculum.
OX NCBI_TaxID=370438 {ECO:0000313|EMBL:BAF58849.1, ECO:0000313|Proteomes:UP000006556};
RN [1] {ECO:0000313|Proteomes:UP000006556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13744 / JCM 10971 / SI {ECO:0000313|Proteomes:UP000006556};
RX PubMed=18218977; DOI=10.1101/gr.7136508;
RA Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.;
RT "The genome of Pelotomaculum thermopropionicum reveals niche-associated
RT evolution in anaerobic microbiota.";
RL Genome Res. 18:442-448(2008).
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DR EMBL; AP009389; BAF58849.1; -; Genomic_DNA.
DR AlphaFoldDB; A5D4I9; -.
DR STRING; 370438.PTH_0668; -.
DR KEGG; pth:PTH_0668; -.
DR eggNOG; COG3383; Bacteria.
DR eggNOG; COG4624; Bacteria.
DR HOGENOM; CLU_018240_2_0_9; -.
DR Proteomes; UP000006556; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR InterPro; IPR006311; TAT_signal.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR PANTHER; PTHR11615:SF345; CATALYTIC SUBUNIT OF IRON-ONLY HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF00037; Fer4; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006556};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..112
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 114..143
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 530 AA; 57982 MW; 79A205983CF86146 CRC64;
MEDSKRGIEQ ENINQEKKEM TRRSFLKMIA GTGLLVGLSG ALAGCVEKSP EHAGGKGWLP
YQYNVAGNLP AQVRGRVPID ADNPSITRDD QKCILCGQCL EVCKNVESVY GYYDLPVVDE
TICINCGQCS MACPSGAISE RDDTKKVFEA LADKDKFVLV QTAPATRVAL GEEFGLPPGT
WVQGQQVAAL RRLGFNAVLD TNFAADLTIM EEATELIKRI KGEVKKPLPQ FTSCSPGWIK
FCEYFYPELI PNISSCKSPQ QMFGALAKTY YARARGIDPE NIVSVSVMPC TAKKFEAQRP
EMNASAKYWK RGNLRDVDVV LTTRELARML KEKQIDLTAL PEENYDKLMG EETGGAVIFG
ATGGVMEAAA RTAYFLITGQ EPPALFLNLT PVRGLAGVKE AAAEIPGVGT LRVAVSHGMA
NGRKILNAVR EGKAPWHFVE FMTCPGGCIA GGGQPRTAVP PSDTVREQRL AALYKADASL
SKRKSYENEE VAALYRDFLG HPMSELAEEL LHTEYHSRAD RLKRILAQAV
//
