ID A5D604_PELTS Unreviewed; 1008 AA.
AC A5D604;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Restriction endonuclease {ECO:0000313|EMBL:BAF58333.1};
GN OrderedLocusNames=PTH_0152 {ECO:0000313|EMBL:BAF58333.1};
OS Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Pelotomaculum.
OX NCBI_TaxID=370438 {ECO:0000313|EMBL:BAF58333.1, ECO:0000313|Proteomes:UP000006556};
RN [1] {ECO:0000313|Proteomes:UP000006556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13744 / JCM 10971 / SI {ECO:0000313|Proteomes:UP000006556};
RX PubMed=18218977; DOI=10.1101/gr.7136508;
RA Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.;
RT "The genome of Pelotomaculum thermopropionicum reveals niche-associated
RT evolution in anaerobic microbiota.";
RL Genome Res. 18:442-448(2008).
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DR EMBL; AP009389; BAF58333.1; -; Genomic_DNA.
DR AlphaFoldDB; A5D604; -.
DR STRING; 370438.PTH_0152; -.
DR REBASE; 15345; PthSORF151P.
DR KEGG; pth:PTH_0152; -.
DR eggNOG; COG3587; Bacteria.
DR HOGENOM; CLU_011799_0_0_9; -.
DR Proteomes; UP000006556; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015668; F:type III site-specific deoxyribonuclease activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR045572; RE_endonuc_C.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF19778; RE_endonuc; 1.
DR Pfam; PF04851; ResIII; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:BAF58333.1};
KW Hydrolase {ECO:0000313|EMBL:BAF58333.1};
KW Nuclease {ECO:0000313|EMBL:BAF58333.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006556}.
FT DOMAIN 64..249
FT /note="Helicase/UvrB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04851"
FT DOMAIN 893..999
FT /note="Type III restriction enzyme C-terminal endonuclease"
FT /evidence="ECO:0000259|Pfam:PF19778"
SQ SEQUENCE 1008 AA; 116366 MW; 22B2C9D8753D9AA6 CRC64;
MKLKFKIQQF QTEAVNAVAD CFAGQPNGQS LFTLDIGQLN SGPQLGISYE VTGFRNRPIE
LTPEEVFENI KKVQVRGGLK ISPKLEGKYN LTVEMETGTG KTYVYIKTMF ELFKRYGWGK
YIVVVPSIAI REGVKKSFEI TEEHFMEQYG RKARYFIYNS RQLHKIDQFA SDPGINVMII
NTQAFNARGK DARRIYMELD EFQSRMPIDV IAQTNPIMII DEPQSVEGTK TVEALKLFKP
LFTVRYSATH RYEYNKVYRL DALDAYNKKL VKKINVKGIN VKGTTGTDGY LYLEGVDISQ
KHYPLARLEF EKKTRSGIKR ELRRVSVNDN LYELSGHLEQ YKGYVVSEIN GGKNTIEFAN
GISLSAGDVL GDVNELTLRR IQIRETIKSH LEKERDLFYR GIKVLSLFFI DEVAKYRQYD
KNGNKLNGEY AQIFEEEYRI LVEEYLRNAG EKDRYADYLR QIDAEKTHNG YFAIDKQGRM
TDPKVKARET DSEDEDAYNL IMKDKERLLS FSEPTRFIFS HSALKEGWDN PNVFQICTLK
HSDSTIKKRQ EVGRGLRLCV NQDGERIDDS VPGIDVHQVN VLSIVASESY DAFARELQRE
IAETLSDRPR KADVQFFLDN VLTNEREEKI RIDERLARKL YQTFVKNNYI DEEDNLTEDY
YQAIEKGAVV LPEELKEHKH AVIKLVSTIY SESASPLVHN ERNKNVELKL NDNFYKEEFQ
KLWKKINVKT AYTVKFDTEE LVDKCINALD TRLRIADISY QIKDGVLEVI DSKEQLERGE
GFVLKEAETG KVDGKVTSGV RYDLAGKLMV ETGLTRKTIV KILTGIKRET FDLFKKNPEG
FILKVARIIN EEKATTIIER ITYDPLKETY DTDIFTQNTL KGMLGENALP VSKHIYNYVI
TDSHTESKFA RDLDASREVC VYAKLPRGFF IPTPVGNYNP DWAIVFEENK VKHVYFIAET
KGSMNSLELR KIEEAKIHCA KKHFEKISNN SVKYGVVENY EKLLEMVS
//
