ID A5D9H3_BOVIN Unreviewed; 470 AA.
AC A5D9H3;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=Transmembrane protein 184C {ECO:0000256|ARBA:ARBA00040417};
DE AltName: Full=Transmembrane protein 34 {ECO:0000256|ARBA:ARBA00042686};
GN Name=TMEM184C {ECO:0000313|Ensembl:ENSBTAP00000013696.4,
GN ECO:0000313|VGNC:VGNC:50109};
GN Synonyms=TMEM34 {ECO:0000313|EMBL:ABQ13032.1};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:ABQ13032.1};
RN [1] {ECO:0000313|EMBL:ABQ13032.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2] {ECO:0000313|EMBL:ABQ13032.1}
RP NUCLEOTIDE SEQUENCE.
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000013696.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000013696.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSBTAP00000013696.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000013696.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Possible tumor suppressor which may play a role in cell
CC growth. {ECO:0000256|ARBA:ARBA00037365}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM184 family.
CC {ECO:0000256|ARBA:ARBA00038513}.
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DR EMBL; BT030592; ABQ13032.1; -; mRNA.
DR Ensembl; ENSBTAT00000013696.5; ENSBTAP00000013696.4; ENSBTAG00000010376.5.
DR VEuPathDB; HostDB:ENSBTAG00000010376; -.
DR VGNC; VGNC:50109; TMEM184C.
DR GeneTree; ENSGT00940000155201; -.
DR HOGENOM; CLU_012923_1_1_1; -.
DR OMA; SLWNPKL; -.
DR TreeFam; TF324245; -.
DR Proteomes; UP000009136; Chromosome 17.
DR Bgee; ENSBTAG00000010376; Expressed in omental fat pad and 105 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005178; Ostalpha/TMEM184C.
DR PANTHER; PTHR23423; ORGANIC SOLUTE TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR23423:SF10; TRANSMEMBRANE PROTEIN 184C; 1.
DR Pfam; PF03619; Solute_trans_a; 1.
DR SMART; SM01417; Solute_trans_a; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 390..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 53391 MW; 9084CCCC68695B15 CRC64;
MRDEKTAQEQ GSALPSTSSF FSFLLGADLC GNMPCTCTWR NWRQWIRPLA VVLYLLSIVV
AVPLCVWELQ KLEVGIHTKA WFIAGIFLLL TIPISLWVIL QHLVHYTQPE LQKPIIRILW
MVPIYSLDSW IALKYPSIAI YVDTCRECYE AYVIYNFMGF LTNYLTNRYP NLVLIIEAKD
QQKHFPPLCC CPPWTMGEVL LFRCKLGVLQ YTVVRPFTTI IALVCELLDI YDEGNFSFSN
AWTYLVIINN MSQLFAMYCL LLFYKVLKEE LSPIQPVGKF LCVKLVVFVS FWQAVVIALL
VKVGVISEKH TWEWQTVEAV ATGLQDFIIC IEMFLAAIAH HYTFSYKPYV QEAEEGSCFD
SFLAMWDVSD IRDDISEQVR HVGRTVMGHP RKKFFPEDQD QNEHTSLLSS SSQDALSVAS
SVPPSPVGHY QGFGHTVTPQ TTPTTANASD DTGNDAAGVR EEPSEKPVAS
//
