ID A5DCU1_PICGU Unreviewed; 569 AA.
AC A5DCU1;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Transcriptional repressor Tup1 N-terminal domain-containing protein {ECO:0000259|Pfam:PF08581};
GN ORFNames=PGUG_01096 {ECO:0000313|EMBL:EDK36998.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK36998.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK36998.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH408155; EDK36998.2; -; Genomic_DNA.
DR RefSeq; XP_001487719.1; XM_001487669.1.
DR AlphaFoldDB; A5DCU1; -.
DR STRING; 294746.A5DCU1; -.
DR GeneID; 5128685; -.
DR KEGG; pgu:PGUG_01096; -.
DR VEuPathDB; FungiDB:PGUG_01096; -.
DR eggNOG; KOG0266; Eukaryota.
DR HOGENOM; CLU_000288_57_23_1; -.
DR InParanoid; A5DCU1; -.
DR OMA; HYLVPYN; -.
DR OrthoDB; 91476at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR001632; Gprotein_B.
DR InterPro; IPR013890; Tscrpt_rep_Tup1_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08581; Tup_N; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00319; GPROTEINB.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 21..97
FT /note="Transcriptional repressor Tup1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08581"
FT REPEAT 308..342
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 343..384
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 384..425
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 433..474
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 486..527
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 528..569
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 109..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 8..99
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 126..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 63114 MW; 19E793C2DD5A0535 CRC64;
MSVYASGNVA QQQQRQQHQQ RLGELLEAVK QEFDFALNEA SNFKQVKEDY DLKYNQQTAE
MQQIRQTVFE LEMAHRKIKE AYEEEILRLK TELENRDRQQ IPGKANGAPF SYIGHQGNQH
SPLPAPLKKE GKKDKDTHTG VTTETSIPPV SAVANSMPAT LQKAPDTSTG IPVIDKTQYV
VDPSQKALHI KEIPPFLCDL DVNKAHPDFK KQKPEYYVLF NPAFSRELDV ELVHSLDHSS
VVCCVRFSKN GEFIATGCNK TTQVFNVATG ELVAKLVDDN TSGHEENGEN DANDSTVQST
NSNGDLYIRS VCFSPDGKLL ATGTEDKLIR IWDLTTKRII KILRGHEQDI YSLDFFPDGN
RLVSGSGDRT VRIWDLRSSQ CSLTLSIEDG VTTVAVSPDG QLIAAGSLDH TVRVWDSTTG
FLVERLDSGI ENGNGHKDSV YSVVFSNDGK QIASGALDRT IKLWNLEGKQ EMNSPGGKRT
TCEVTYVGHK DFVLSVCSTL NNEFILSGSK DRGVVFWDQL SGNPLLMLQG HRNSVISVAV
SLNSNGTEGI FATGSGDCKA RIWKWTRKQ
//
