ID A5DFA9_PICGU Unreviewed; 403 AA.
AC A5DFA9;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Carnosine N-methyltransferase {ECO:0000256|ARBA:ARBA00015448};
DE EC=2.1.1.22 {ECO:0000256|ARBA:ARBA00012003};
GN ORFNames=PGUG_01960 {ECO:0000313|EMBL:EDK37862.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK37862.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK37862.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the carnosine N-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010086}.
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DR EMBL; CH408156; EDK37862.2; -; Genomic_DNA.
DR RefSeq; XP_001486289.1; XM_001486239.1.
DR AlphaFoldDB; A5DFA9; -.
DR STRING; 294746.A5DFA9; -.
DR GeneID; 5127736; -.
DR KEGG; pgu:PGUG_01960; -.
DR VEuPathDB; FungiDB:PGUG_01960; -.
DR eggNOG; KOG2798; Eukaryota.
DR HOGENOM; CLU_030612_0_0_1; -.
DR InParanoid; A5DFA9; -.
DR OMA; GSMSMCA; -.
DR OrthoDB; 167229at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR012901; CARME.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12303:SF6; CARNOSINE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12303; UNCHARACTERIZED; 1.
DR Pfam; PF07942; CARME; 1.
DR SMART; SM01296; N2227; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 403 AA; 45850 MW; 6CB3F69B1351DE5D CRC64;
MADEEWNALS GTLAAFHNFH RWSYEEVVKP RRIREASMKE SEKNLLSWYS KHTSDLAEAV
QLNSHFCSGL AGVAASQWGV GADPTVWAEP SGSDFDKVRS TLLQLCREWS SDGVKEREVS
FGRILNEALE RYPEVTHRPE VNVLVPGCGL GRLVYEFVHH GFKCQGNEFS YHMLLTSNYI
LNNCQFANEH SILPYIYKAS HVQKRSLQLR PVTVPDVSAR DIHDLQAHLP NVDISELMSM
AAGSFTELYG PEEIQPVEEV QSDDAIQFRQ SVQGTFDILC TCFFLDTASN IVDYLKTIRH
CLKKTSGIWI NFGPLLWHFE DDANVEYKSL VLKEGDEPRK VATTRKGMEL SLEDLLQLMK
NMGFTLDKHE SGIKTTYSGD PRAMGGYVYE CEYWVARVEE KTE
//
