ID A5DFL4_PICGU Unreviewed; 366 AA.
AC A5DFL4;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=t-SNARE coiled-coil homology domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PGUG_02065 {ECO:0000313|EMBL:EDK37967.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK37967.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK37967.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the SEC20 family.
CC {ECO:0000256|ARBA:ARBA00037934}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408156; EDK37967.2; -; Genomic_DNA.
DR RefSeq; XP_001486394.1; XM_001486344.1.
DR AlphaFoldDB; A5DFL4; -.
DR STRING; 294746.A5DFL4; -.
DR GeneID; 5127769; -.
DR KEGG; pgu:PGUG_02065; -.
DR VEuPathDB; FungiDB:PGUG_02065; -.
DR eggNOG; ENOG502S7WD; Eukaryota.
DR HOGENOM; CLU_051527_0_0_1; -.
DR InParanoid; A5DFL4; -.
DR OMA; NTIMHES; -.
DR OrthoDB; 2055360at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR InterPro; IPR005606; Sec20.
DR PANTHER; PTHR12825; BNIP1-RELATED; 1.
DR PANTHER; PTHR12825:SF0; VESICLE TRANSPORT PROTEIN SEC20; 1.
DR Pfam; PF03908; Sec20; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 124..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 366 AA; 41435 MW; F082DC71D28F100F CRC64;
MIASDILRPG DIERCFHGLQ VLQNEAFSQI ASIAVTDDDY EGSIESRRTK ITRRVQQTLN
NYRDLLDILK AELNSSGNYD FYKEDYLAYQ QKLGHLRVRL RESQLLSSAR EREIIHQARI
DKYAPRPKSP DHTEAREQLF AGRSTTKTKE TVDDQIFAHN KSITAALQST RQMMASSVVQ
TGLNIDNLDQ QTQDIAQLSF KLSDLTATLE KSKNIVRFIE KQDKQDKKRI YISIGFLLLC
SAWILWRRIF RLPVRLLFWT IMKVFRVFSW FLPNMNFDYS ASKMDTAAIS SPIVETLLSS
TSTSLSASSI SSISSISSIS SSSISSALES AISVVSDIVI DIDTNNVAST WEDVVSTALQ
YAKDEL
//
