ID A5DK13_PICGU Unreviewed; 922 AA.
AC A5DK13;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=OPT family small oligopeptide transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=PGUG_03614 {ECO:0000313|EMBL:EDK39516.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK39516.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK39516.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oligopeptide OPT transporter family.
CC {ECO:0000256|ARBA:ARBA00008807}.
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DR EMBL; CH408158; EDK39516.2; -; Genomic_DNA.
DR RefSeq; XP_001484233.1; XM_001484183.1.
DR AlphaFoldDB; A5DK13; -.
DR GeneID; 5125823; -.
DR KEGG; pgu:PGUG_03614; -.
DR VEuPathDB; FungiDB:PGUG_03614; -.
DR eggNOG; KOG2262; Eukaryota.
DR HOGENOM; CLU_004965_1_0_1; -.
DR InParanoid; A5DK13; -.
DR OMA; KWKFKVW; -.
DR OrthoDB; 2782392at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR004648; Oligpept_transpt.
DR InterPro; IPR004813; OPT.
DR NCBIfam; TIGR00727; ISP4_OPT; 1.
DR NCBIfam; TIGR00728; OPT_sfam; 1.
DR PANTHER; PTHR22601; ISP4 LIKE PROTEIN; 1.
DR PANTHER; PTHR22601:SF9; OLIGOPEPTIDE TRANSPORTER 2; 1.
DR Pfam; PF03169; OPT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptide transport {ECO:0000256|ARBA:ARBA00022856};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..729
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 749..766
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 778..800
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 812..841
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 853..876
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 922 AA; 104089 MW; 19D5E0B3EDA93BF8 CRC64;
MSVSPVRSTI SPLAGITSTG SRLNAVDHEV DLSALQSSDI ALGDVGASFT EDQKFFILRR
MYLDGLLSLE HLPPSATFLI EKMESLTEEE SLEILREYLV NFEDDCNIST ADYNLIQRLV
ALAAADFGTS DGIKEKLGRQ IDGKSEAADD SVEVGSSSAV DEDLPKADIQ YEYHKITDLP
FQLKVEVGLI AYHSPYATVR SVTEPYDDPT VPCETIRVYV VGIIWTAVGS VINQFFIERQ
PSISFDASVA QVFIYPSGVL LSYILPKWSL KVWKYSFDLN PGPWTYKEQM LATLCYSISG
ASPYAASNIL VQKMPIFYNN QWVDFGYQVL LILSSQFLGF GLAGIMRRFV VYPVQSIWPT
ILPTIALNKA LTLPEKKENI HGWTISRYYF FFATFFGSFL YFWIPNYLAQ FLSTFNWMTW
IKPTNLNLAN ITGSVSGLGL NPISTFDWNI LNYGLPLTIP FYSTMNQTIG WIVGFVSIVG
VYYSNHLWTQ YIPINTNGLY TNTGKPYAVT QVLNEKGLFD EAKYQEIGPP FYSAASLVGY
GAFFAIYPFA FVYELVVNWK VNSFALKSLF QTIKNFHRSN YEGFNDPFSR SMARYKEVPD
WVFILILVIS IVLSILCVKL YPAETPVWGI FFALGINFVF LIPLASIYSR TGFSFGLNVL
VELIVGYALP GNGLALMYIK AIGYNIDGQA ENYITNQKLA HYVRIPPWSI FRVQIVSVFI
CCFITLGILS FQMNDINDYC DPLNKQKFTC AYSRTFYAAS VLWGVIGPKR VFNGLYPILR
YCFLIGFLLT IPAILFKWYG PKKYTKYFQP TVIIGGCTVF APYNLSYFIG GLYLAIAFMW
YLKERKPGWW EKYNYLFSAG MTAGVAFSGI IIFFAVQYHD KSIIWWENTV MYAGLDGLGV
AALNATISAP DGYFGPRKGH FP
//
