ID A5DPV8_PICGU Unreviewed; 776 AA.
AC A5DPV8;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 2.
DT 24-JAN-2024, entry version 81.
DE RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
GN ORFNames=PGUG_05309 {ECO:0000313|EMBL:EDK41211.2};
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746 {ECO:0000313|EMBL:EDK41211.2, ECO:0000313|Proteomes:UP000001997};
RN [1] {ECO:0000313|EMBL:EDK41211.2, ECO:0000313|Proteomes:UP000001997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL
RC Y-324 {ECO:0000313|Proteomes:UP000001997};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408161; EDK41211.2; -; Genomic_DNA.
DR RefSeq; XP_001482289.1; XM_001482239.1.
DR AlphaFoldDB; A5DPV8; -.
DR STRING; 294746.A5DPV8; -.
DR GeneID; 5124307; -.
DR KEGG; pgu:PGUG_05309; -.
DR VEuPathDB; FungiDB:PGUG_05309; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_0_3_1; -.
DR InParanoid; A5DPV8; -.
DR OMA; GMIMFPI; -.
DR OrthoDB; 204198at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR43310:SF4; SULFATE TRANSPORTER; 1.
DR PANTHER; PTHR43310; SULFATE TRANSPORTER YBAR-RELATED; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 422..536
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 776 AA; 86670 MW; 0E6AA99C4788DF55 CRC64;
MFYVSCIVSQ LVYSLGGSAF KSGIGSEMIE VTPFFHTMAY SIMNEMKGAP DNAVIATTIV
AFAMSSIVTG IVFFSLGKLK LGKLVGFFPR HILVGCIGGV GFFLIMTGIE VSSRLEGGME
FTVPALKYLF SNHVTLLQWT IPLALAIFLI ILQHRFHNSL LVPLFFICVF AIFHLIVKFI
PKYNLKMVRD SGWVFPAVED NQPWYAFYEL YKFQLVDWWA ISKQFPSMLA LTFFGILHVP
INVPALAVTV GMDQCDVDRE LVAHGYSNAI SGLVGSIQNY LVYTNSVLFI RAGADDRVAG
VLLAIATGAV MVAGPVVIGY IPVCVVGSLI YLLGYELLKE ALYDTWGRLR RIEYTTIAII
VLVMGVWDFV YGVLVGILLA CLLYVVEAAQ RPVIRGIYTG VVARSTVLRH PKQQEFLKDV
GDQICVVKLE GSVFFGSIGG VESEIRKRFE GESFKETPIK FLILDMKGVA SIDFSAAEGF
RRILNLTTEK GTQLVISSVE ENDSIVVALR DAGLWEKPTD MPIQLFNTLN YALEWCENSF
LAMYKSVKKE QRIPINPALG MSTYERHKSI SPTNTGINKS LMGQAVGMTY GTPRTNQVYQ
AATRTVNDEQ KIQNKYFGSQ DSTFKKQPLP LLMLTFSGLS NMDEKFWSLL ASYFVKETIP
EDITFYDTAK DSPSFFLVES GLIRSVCKFE SDDRELHSSI LPLTAFGDLY HKGSQFRDMA
YTTVNYTVTW RLTEKKLAEL MKAPGGEALY NELLKIQIKL VRERFDTMTA NLVISA
//
