ID A5DRR0_LODEL Unreviewed; 635 AA.
AC A5DRR0;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=XPG-I domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LELG_00046 {ECO:0000313|EMBL:EDK41868.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK41868.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK41868.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981524; EDK41868.1; -; Genomic_DNA.
DR RefSeq; XP_001527526.1; XM_001527476.1.
DR AlphaFoldDB; A5DRR0; -.
DR STRING; 379508.A5DRR0; -.
DR KEGG; lel:LELG_00046; -.
DR VEuPathDB; FungiDB:LELG_00046; -.
DR eggNOG; KOG2520; Eukaryota.
DR HOGENOM; CLU_015323_0_0_1; -.
DR InParanoid; A5DRR0; -.
DR OMA; QCAYLQK; -.
DR OrthoDB; 1779469at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProt.
DR CDD; cd09870; PIN_YEN1; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081:SF54; FI23547P1; 1.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001996}.
FT DOMAIN 1..108
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 135..201
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 558..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 72542 MW; 0ED9B4721547E501 CRC64;
MGVAELWDIL KTASSPRVPL EVFVDQFILE HGRTPRVAID AYMFIFQLDH SAIPLEEKAH
IVVQNFMSKI LALISLNVSV IVVFDGCCKP DKSKSGNGTL LYEDQFREFT VKVANNERNF
SEEIPIVEEI KELLRLNSIL YCQAPGEGEA QCAHFQRLGV VDFVMSNDVD TLVFGATKML
RNYSRFLEDI GLSPLKKQAT LKTRYYVTPI EMDKVEAVTG FSRSRLVFLA SLRGGDYSSG
VQRIGITNAK YLALCGTKYG LFYNQQSVQA KTTKHLVLRN TPRKYSTKVP PPDFATEFIA
CFVEVTEEVG PLWDSRLSEA SRMKNLHEFS TRFASILNGS NSHIFGRNLT LKDTINLNEY
YTLLYLFPFV DTQLPLFAPN MLSSGEFTSP FANDNGSLTA GETLQDTGLY VPESYNCLVK
HIIFKLIKNL NLSIVKDREN EVQFIYNVSD VSRRFPNSIE NRRLMFEGSL ESKSGFLWVP
VSLVKLFYPQ LLQQYYQEKK DLEYYKKHKF SPQKTTLDML ENSPTKATKR HQTSVINLEP
IPFQMVATES IEQKSFSERS STSINFKRSF SPSRRSSSPS RRNDSPTRRS NSPTRRNRSP
ARKKLDPNQK TLEFFLDKPK LEAESNPFFI DLTKD
//
