ID A5DU25_LODEL Unreviewed; 690 AA.
AC A5DU25;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 22-FEB-2023, entry version 75.
DE RecName: Full=DOC domain-containing protein {ECO:0000259|PROSITE:PS51284};
GN ORFNames=LELG_00861 {ECO:0000313|EMBL:EDK42683.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK42683.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK42683.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the APC10 family.
CC {ECO:0000256|ARBA:ARBA00006762}.
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DR EMBL; CH981524; EDK42683.1; -; Genomic_DNA.
DR RefSeq; XP_001528341.1; XM_001528291.1.
DR AlphaFoldDB; A5DU25; -.
DR STRING; 379508.A5DU25; -.
DR GeneID; 5235673; -.
DR KEGG; lel:LELG_00861; -.
DR VEuPathDB; FungiDB:LELG_00861; -.
DR eggNOG; KOG3437; Eukaryota.
DR HOGENOM; CLU_025279_0_0_1; -.
DR InParanoid; A5DU25; -.
DR OrthoDB; 20429at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd08366; APC10; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR016901; APC10/Doc1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR12936; ANAPHASE-PROMOTING COMPLEX 10; 1.
DR PANTHER; PTHR12936:SF0; ANAPHASE-PROMOTING COMPLEX SUBUNIT 10; 1.
DR Pfam; PF03256; ANAPC10; 2.
DR SMART; SM01337; APC10; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS51284; DOC; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996}.
FT DOMAIN 380..585
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..222
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 75888 MW; 9615F76567326477 CRC64;
MNSSGYWDRS SVGHSNSPNT SSIFISHDAD AGEEAERAQD QNLPPAPTLI LTPAPAPASA
SASASTSAPI PARAHAPGSA PVALLALLAL LGLLIPLSTT PSADDASLAH VGPYFDITPH
PNQHEVQMQP QYTPEEIRCS LGSGVLTDEQ ASRIHHHNFM QLIEEDEEEL DDYYVNGTSR
LGAGLLASRV IGDGGDGDDS GDSENNVVDA DDPIDASDFN EVDDADDRFN GSFSRIGGLA
TGITTIVPDT QRSTWEGIMT TEDRRQQLRL MQQTLETYPL QNILTIEEGD EHVNESNIID
GMSSEREVRD NDTDHDMLSH GTTSSVGQEQ LEQQQQQQQQ QHHHHHHNQD HYQQLHHRPL
EHEVDDDNEI NADESHSQPS LEQVQRVYYT KGLEELESLQ LVDLSALATW KLSSFKPGFG
LSQLRDDSPE TYWQSDGSNG GNNTIPSNSA FTNNHLSNPH SVTIQFIKRV ALERISIFTN
YSLDESYTPS KIKIMAGSSE GWDLIDVCTV NFNQPIGWSH IIFNGIRNDG VLKCFMVKIF
ILANHQEGKD SHIRAIRCFG RKHSVPPVKG LPSIGNPYHD YNHNHNNSIP HRVNPELLRD
LSIASGSSLN SGILVGNRII SNSSDVRHQT EVDAEVDAEA ESLVLLPLLP QFPKQTLNEE
TTSAMRNVNA VLGLNSGFKS IELSSVSSIR
//
