ID A5DZG4_LODEL Unreviewed; 539 AA.
AC A5DZG4;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Guanine nucleotide-binding protein alpha-3 subunit {ECO:0000313|EMBL:EDK44572.1};
GN ORFNames=LELG_02751 {ECO:0000313|EMBL:EDK44572.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK44572.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK44572.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981526; EDK44572.1; -; Genomic_DNA.
DR RefSeq; XP_001526193.1; XM_001526143.1.
DR AlphaFoldDB; A5DZG4; -.
DR STRING; 379508.A5DZG4; -.
DR GeneID; 5233161; -.
DR KEGG; lel:LELG_02751; -.
DR VEuPathDB; FungiDB:LELG_02751; -.
DR eggNOG; KOG0082; Eukaryota.
DR HOGENOM; CLU_014184_0_2_1; -.
DR InParanoid; A5DZG4; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR002975; Fungi_Gprotein_alpha.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF363; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR01241; GPROTEINAFNG.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 60481 MW; 5FF3474FF49712D6 CRC64;
MGLCSSKDAS EKNTPHSQQT TQLKRQEQRL ALQQQQQQQN QQTSPQQLSQ PENLNHIAPK
HEAIGSGSDV DHSNGSTLST GDPLSTTTAN GNDRHLQQQQ QQQQQQQQQQ YVQEQQVSTP
KINQSKKSND ATVTSTLNGS RSSTNQNPVD IAARLNTLKE VKILLLGSGE SGKSTVVKQM
KILHQEGFSV EELYEYKPFV YKNIMDCIKN VINAIIELQP ELIKPNAKID DVNGVANGEV
GNGHADAAAM TGASNGTTTI SNKINNNIEN TTAVQPHMHV LDYDALQEVL NYEIILDGTN
DTTFDAEIAS KIEAIYNHPE VKEFMIHKQG QFYLIDSTEY FLTNLHRIVQ PDYIPSTTDI
LHTRKKTSGI FDFNFDMGNG LNIHLFDVGG QRSERKKWIH CFDNVTLIIF CVALSEYDQV
LLEENNQNRL EESLALFDSV VNSRWFARTS IVLFLNKIDV FAEKLQYSPL EAHFPDYTGG
NNINKAAKYI LWRFNQVNRS GLNIYPHVTQ ATDTSNIKLV MAAVKETIME NSLKDSGII
//
