ID A5E101_LODEL Unreviewed; 445 AA.
AC A5E101;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 24-JAN-2024, entry version 89.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LELG_03288 {ECO:0000313|EMBL:EDK45109.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK45109.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK45109.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981527; EDK45109.1; -; Genomic_DNA.
DR RefSeq; XP_001525360.1; XM_001525310.1.
DR AlphaFoldDB; A5E101; -.
DR GeneID; 5232648; -.
DR KEGG; lel:LELG_03288; -.
DR VEuPathDB; FungiDB:LELG_03288; -.
DR eggNOG; KOG0703; Eukaryota.
DR HOGENOM; CLU_031494_1_0_1; -.
DR InParanoid; A5E101; -.
DR OMA; FQNLQVS; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08204; ArfGap; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF9; PROTEIN GTS1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 11..134
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 188..231
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 239..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 445 AA; 50290 MW; B32743BDD288B3C9 CRC64;
MSRRYQKNIE KQLLDLVNER GNNNKCGECG TGYPTWASYN LGIFLCGRCA SVHKRILGPP
HNDISKVKSL TLDHWNEDQV RRLGKIGNQK ARRKWNSKKV PFPFDGDDDI AVVEQYIRDK
YILGKFRDND DVDPSEFDDR LSSGYDSHLR PSMGLRQGLR LKLRLRSNSA FSVYQIPKLT
HRKLTTFEYT QYNAQADKIR GYGYNDRDAV LESLLLSNGN VDKALDILDQ DTRINPAKEE
IAPSLPSRPR PQAQPQSQSQ SQSQISTTSS ATPSTSDWWS GNQPPSANSA NLSTMTTGVQ
QPQIYQYTDP VTGQITYVDS NGQEYLDPNN PQHQQQLMNI SNPQLIAQQT NKQNILSLYN
NPTGVQQPQQ TVQQQFGIQQ TGFGPQQTGF LPQQPTQFTA FSPGQQQPVP PPPSQQQQQQ
QSQFTGFGQP QQTGYFGQPQ QGYFR
//
