ID A5E257_LODEL Unreviewed; 788 AA.
AC A5E257;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Bromodomain-containing factor 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=LELG_03694 {ECO:0000313|EMBL:EDK45515.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK45515.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK45515.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981528; EDK45515.1; -; Genomic_DNA.
DR RefSeq; XP_001524662.1; XM_001524612.1.
DR AlphaFoldDB; A5E257; -.
DR STRING; 379508.A5E257; -.
DR GeneID; 5232154; -.
DR KEGG; lel:LELG_03694; -.
DR VEuPathDB; FungiDB:LELG_03694; -.
DR eggNOG; KOG1474; Eukaryota.
DR HOGENOM; CLU_001499_4_0_1; -.
DR InParanoid; A5E257; -.
DR OMA; PITYEMQ; -.
DR OrthoDB; 152619at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd05500; Bromo_BDF1_2_I; 1.
DR CDD; cd05499; Bromo_BDF1_2_II; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF225; BROMODOMAIN-CONTAINING PROTEIN BET-1; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51525; NET; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 270..342
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 448..520
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 643..722
FT /note="NET"
FT /evidence="ECO:0000259|PROSITE:PS51525"
FT REGION 1..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..251
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..625
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 788 AA; 88675 MW; ADBDEEC969292928 CRC64;
MSQGIAAETH TPVQTPSADG SIHQDDNINN SGNDSNNSNN NNDDNSDKIS TVHDSKPLNG
VKGSINENAE ENSSHQKHEH EPLSPPNPSP TPEKRKLEEE SSDTAEKDVV PEEKADSVEP
EAKKQKVEET EATDTSHTSA GLETNGAESV EKSALLSPTA TGPTPDDEIK EEPKLDEEKP
EEKFEDKSEE KSEDKSEEKS EDKQEEKTEE KQEEKSEEKQ EEKSEDTTEV QQPLEPAPKP
PSEPDMNNLP EHPLPPHQTK FALNTIKAIK RLKDAAPFLH PVDTVKLNIP FYYNYIPRPM
DLSTIERKLN AKAYEDISQF ADDFNLMVAN CKKFNGETAG ISRMATNIQA HFEKHMLNAP
PKELPVGVAT HTSASSPEAV TPTSKRRVAA ETNAQHQHRD SVAAARPKRT IHPPKSKELP
YDVRPRKKKF AAELRFCGQT IKELMSKKHQ NYNFPFLAPV DAVALNIPNY HDIVKHPMDF
GTIQSKLTNN QYESGDDFEK DVKLVFHNCY LFNPEGTDVN MMGHRMEAVF DKKWAQKPIP
EPTPPPSDHS DVEDIVSEEE EEVSEAMLSE VPAIQFLENQ LTRMKKELDE LKKEHLKKLR
EQQAARRKRK RAQSVSKRGS KSKKGHKESS HSSSNHNSHH RHQVKLTPPQ PVVTYEMKKQ
VSEMVPNLSD KKLNALIKII QDDVQISNDD EVELDMDQLG DSTVLKLYDF LFGEKATQKS
SLQQQHKKRL NKASANLDEL AHLRSQLALF DEGNGHSAEH QLENNGFMSI THEESSDDAA
SSESSEEE
//
