ID A5E3Y0_LODEL Unreviewed; 607 AA.
AC A5E3Y0;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=LELG_04318 {ECO:0000313|EMBL:EDK46138.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK46138.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK46138.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981529; EDK46138.1; -; Genomic_DNA.
DR RefSeq; XP_001524347.1; XM_001524297.1.
DR AlphaFoldDB; A5E3Y0; -.
DR STRING; 379508.A5E3Y0; -.
DR GeneID; 5231469; -.
DR KEGG; lel:LELG_04318; -.
DR VEuPathDB; FungiDB:LELG_04318; -.
DR eggNOG; KOG1842; Eukaryota.
DR HOGENOM; CLU_026440_1_0_1; -.
DR InParanoid; A5E3Y0; -.
DR OMA; ARCCEAC; -.
DR OrthoDB; 1441111at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15761; FYVE1_Vac1p_like; 1.
DR CDD; cd15737; FYVE2_Vac1p_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR021565; Rbsn_Rab-bd.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR39490; ARRESTIN DOMAIN-CONTAINING PROTEIN D; 1.
DR PANTHER; PTHR39490:SF12; FYVE ZINC FINGER FAMILY PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF11464; Rbsn; 1.
DR SMART; SM00064; FYVE; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS50178; ZF_FYVE; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 129..203
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 298..384
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 548..601
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 68976 MW; 6E1645743F3DDC90 CRC64;
MSDNISNSNS KSDSATPALS ATAVTSSVSS TSNSKSPSPR RNTPAKKINK IVFSEHGFSI
GDIQRSRSSS PTSRSRSESP AVSTELSEAS GVSGVSGVSR VSRASAKSRA TSSSLSAHII
TSHWKQQSSV SDPRCKICGK KLNVKNGIVN CRKCGELYCN EHTHYQVKLR NPDPQHGETK
PQFDTSAHGI WCRCCELCYM ERRKTEVNFV DVTLDFKQKR QEHVDQRELH ETKVQRNFIK
LTNLMVDKSL LKRAKGGKKG NLEGLGKINS TSNGIFSFFK PVSNDEMSII GADNWVPDDN
ATNCTICFTK FNFIIRKHHC RLCGEVVCDD SSGVRKNCSL YVPLVAFLEK LPNLNYSSQV
RKHWSEIDQE LRFRCCVNCK NAVLHDWKRV HRGQIGSAST IGGTDVEGEE IFRMYDGMLL
QKGLIEQMMH QYEFGSRSGI TKVGGTGSDG EDEMKTGHKL MLYLKEFENL VIQFKKKFFF
KDNDKLLIQQ EYLNFERVLL NMYQSVGTFL QNNIIKFKAI QEERRPKIEQ ALPEKEETPV
PRLTKKQIRE LREQLMVLNE QKFLIENQIQ EFTRNRQFDE LNTLITNKDE ILDTIKQVEN
ELGEFGF
//
