ID A5E6A4_LODEL Unreviewed; 510 AA.
AC A5E6A4;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 22-FEB-2023, entry version 67.
DE RecName: Full=Programmed cell death protein 2 C-terminal domain-containing protein {ECO:0000259|Pfam:PF04194};
GN ORFNames=LELG_05143 {ECO:0000313|EMBL:EDK46962.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK46962.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK46962.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981531; EDK46962.1; -; Genomic_DNA.
DR RefSeq; XP_001523727.1; XM_001523677.1.
DR AlphaFoldDB; A5E6A4; -.
DR STRING; 379508.A5E6A4; -.
DR GeneID; 5230709; -.
DR KEGG; lel:LELG_05143; -.
DR VEuPathDB; FungiDB:LELG_05143; -.
DR eggNOG; KOG2061; Eukaryota.
DR HOGENOM; CLU_031771_0_0_1; -.
DR InParanoid; A5E6A4; -.
DR OMA; LMPKMIL; -.
DR OrthoDB; 5397827at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR InterPro; IPR007320; PDCD2_C.
DR PANTHER; PTHR47524; 20S RRNA ACCUMULATION PROTEIN 4; 1.
DR PANTHER; PTHR47524:SF1; 20S RRNA ACCUMULATION PROTEIN 4; 1.
DR Pfam; PF04194; PDCD2_C; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001996}.
FT DOMAIN 372..506
FT /note="Programmed cell death protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04194"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 133..164
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 56324 MW; 501270379E4A18DF CRC64;
MSSSKSNYIH DSNNSSSNSN NDDEYFSSDD ESIYDGGSNS KVVLGFVDAP ITADDQPSIE
DTFIGGQPVW LHPDSKPDEQ YLICNHCNKK MALLSQAFAP IDGILYDRVL YIFGCKNPGC
SRQKGSVKVI RGIDKSAETV SRIKSELEDA KAKELDEKLK LDNKKQLNQE LMKDLFKKPD
AESSQGGGTN PFGAQNPFAK SGDKDSNPFG SNPFAKPEEN KSNDLQSMTT QQKKQEAAME
KVTKPVSKSK PTKENEQPKE SQSFAEVVAQ NAPKQVETKV KTLEGDLPEY IGNFVFVEPE
KFKKDKTSDA ELAKYKHLIE KNNSEGNGGS GAGGDDDDGI FGLGGGSSSR RGSQSSAVLD
PQTQGISNML DDKYFENFSS TVKHNPGQVL RYDLHGRPLL YNGKDDVAKR FLVNPPNIPR
PGYNPSSERR FELQLMPKAI MDLEGLDIDG DEKEGRGNSK VDIKDILNGM SWGTIIVCTD
VEDYIPDDRF DENGVAYIEE WCGVQWEESV
//
