ID   A5E7U9_LODEL            Unreviewed;       528 AA.
AC   A5E7U9;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   03-MAY-2023, entry version 71.
DE   RecName: Full=Enhancer of mRNA-decapping protein 3 {ECO:0000256|ARBA:ARBA00015797};
GN   ORFNames=LELG_05688 {ECO:0000313|EMBL:EDK47507.1};
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK47507.1, ECO:0000313|Proteomes:UP000001996};
RN   [1] {ECO:0000313|EMBL:EDK47507.1, ECO:0000313|Proteomes:UP000001996}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC   NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA   Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA   Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA   Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA   Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA   Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA   Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC       {ECO:0000256|ARBA:ARBA00004201}.
CC   -!- SIMILARITY: Belongs to the EDC3 family.
CC       {ECO:0000256|ARBA:ARBA00006610}.
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DR   EMBL; CH981534; EDK47507.1; -; Genomic_DNA.
DR   RefSeq; XP_001523142.1; XM_001523092.1.
DR   AlphaFoldDB; A5E7U9; -.
DR   STRING; 379508.A5E7U9; -.
DR   GeneID; 5230245; -.
DR   KEGG; lel:LELG_05688; -.
DR   VEuPathDB; FungiDB:LELG_05688; -.
DR   eggNOG; KOG2585; Eukaryota.
DR   HOGENOM; CLU_037134_0_0_1; -.
DR   InParanoid; A5E7U9; -.
DR   OMA; AMFDKKS; -.
DR   OrthoDB; 1409462at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.30.30.100; -; 1.
DR   Gene3D; 3.40.50.10260; YjeF N-terminal domain; 1.
DR   InterPro; IPR025762; DFDF.
DR   InterPro; IPR019050; FDF_dom.
DR   InterPro; IPR004443; YjeF_N_dom.
DR   InterPro; IPR036652; YjeF_N_dom_sf.
DR   PANTHER; PTHR13612:SF0; ENHANCER OF MRNA-DECAPPING PROTEIN 3; 1.
DR   PANTHER; PTHR13612; UNCHARACTERIZED; 1.
DR   Pfam; PF09532; FDF; 1.
DR   Pfam; PF03853; YjeF_N; 1.
DR   SMART; SM01199; FDF; 1.
DR   SUPFAM; SSF64153; YjeF N-terminal domain-like; 1.
DR   PROSITE; PS51512; DFDF; 1.
DR   PROSITE; PS51385; YJEF_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001996}.
FT   DOMAIN          128..164
FT                   /note="DFDF"
FT                   /evidence="ECO:0000259|PROSITE:PS51512"
FT   DOMAIN          259..503
FT                   /note="YjeF N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51385"
FT   REGION          65..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   528 AA;  58347 MW;  D4B2BD4EE46A7E27 CRC64;
     MADFLHCKVN LNLKDGSTST GTITFVDNNQ ITLKDATNTI DPSISFPSIT IPNAKVADLK
     ILQVPSTSNG NGNGNNNSNS KKRSKAKNSE LVDDAILFAS KPSRSTTPKP KSSGESSHGT
     NGKPEKSLAL DVDDVKNSEF DFQANLAMFD KKSVFDSFRK NDHTQLSDRL VGQNKIENIA
     KPKKEKYDNN EMVLDSQPKD NWDSIGKSID RQKTETPTDS VKNHGAQRQL SQERIKMKNF
     ALVNAGDLKP MQTASPVQLL EIERLAEDVF GVSPTMMTEA CATNLSKLII DTCLGGSIRL
     SNKSNHNLPP LVLLLIGSGR CGSRAFATGR HLNNHGVRVL AFVISSDDSD KELHQQWQSF
     EAAGGKVISS NFDELVDIIQ NQLNTPVELI IDALQGYDDH LEDIFYELEN QKTLQKVINW
     CSNPQQQQKI MSLDLPSGID GGSGTLSDEN TKIECRWCIS MGLPLSGIIL AYKNGVMEHQ
     DVGGHHEILH YLVDVGIPNK VYLMKPNLRK FDKFWYCAET CIKLDVAV
//