ID A5E7Z1_LODEL Unreviewed; 725 AA.
AC A5E7Z1;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=LELG_05730 {ECO:0000313|EMBL:EDK47549.1};
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508 {ECO:0000313|EMBL:EDK47549.1, ECO:0000313|Proteomes:UP000001996};
RN [1] {ECO:0000313|EMBL:EDK47549.1, ECO:0000313|Proteomes:UP000001996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC NRRL YB-4239 {ECO:0000313|Proteomes:UP000001996};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH981534; EDK47549.1; -; Genomic_DNA.
DR RefSeq; XP_001523184.1; XM_001523134.1.
DR AlphaFoldDB; A5E7Z1; -.
DR STRING; 379508.A5E7Z1; -.
DR KEGG; lel:LELG_05730; -.
DR VEuPathDB; FungiDB:LELG_05730; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_021752_0_0_1; -.
DR InParanoid; A5E7Z1; -.
DR OMA; NPQKEQD; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:UniProt.
DR CDD; cd07627; BAR_Vps5p; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035803; BAR_Vps5.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR PANTHER; PTHR10555; SORTING NEXIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001996}.
FT DOMAIN 320..442
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 725 AA; 81939 MW; 1EB24013088851B9 CRC64;
MDDLTKSVWD DEESTSIGDG RNTTLQYDQV NEPHTSTFNP ASSSSSVTAP LISTFNSFSI
DDPFANPFSD DKPQEEVEEE EEEKQEGFRE QKQEQGQEKH NENNELEGGE QDDDFFKAGK
VNGASDNGLY SPRKHHLQSQ ILSELTEGSD SFDLEQSLTK PTASKNILKS DQLFSDKDSP
IKLSSSDQSS ISSPSSVGPI NLKKFKAKRP RRFDSKTNVQ HLKGELENVN SNLLGPLTFE
NKQKRDKEEE KDVGNQGAQK EPTELTTEAI GNQMGTIHEE LQGNKKNSNN SPSKQKTTPK
NTTKNTETNS YAEAPLKNDN QLEITVGDPM KVGDITTAHI MYTIKTRNKN LDSPNFPQIK
EVSVQRRYSD FRWLFHQLQA NHPGRIIPPP PAKQSLIGRF NEKIIEHRRL SLEKMLNHIN
TKPLLCNDPD FVSFLTNENE GHAFGDASLD ESAIQDGHSS VSSSFTTPTS TTTTTTTTTT
ATAAANAANA AASAAFASTG FMSSLFSLST KYTEPDSYFT KKKQYFDDLE YNLKQLLKTL
ELIGTQRLDL LNIWEEIAIT MEELAAVEIT KSTSDLFNAF SQVQYHIKDN IERLNLSDQL
TMGFTVEEYL RLIDAINYTF KTRIKIFELL SSLNAQVDKL SRKLSLLPEK SFELERMKER
QSSLQKDFNE ISNTIKLELD EFEMTRIDDF RNNVEIYIEN AIESQKEAIE VYETFYSRYI
AVDNE
//
