ID A5FI50_FLAJ1 Unreviewed; 1568 AA.
AC A5FI50;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Nonribosomal peptide synthetase {ECO:0000313|EMBL:ABQ05120.1};
GN OrderedLocusNames=Fjoh_2090 {ECO:0000313|EMBL:ABQ05120.1};
OS Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC
OS 14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=376686 {ECO:0000313|EMBL:ABQ05120.1, ECO:0000313|Proteomes:UP000006694};
RN [1] {ECO:0000313|EMBL:ABQ05120.1, ECO:0000313|Proteomes:UP000006694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 /
RC UW101 {ECO:0000313|Proteomes:UP000006694};
RX PubMed=19717629; DOI=10.1128/AEM.01495-09;
RA McBride M.J., Xie G., Martens E.C., Lapidus A., Henrissat B., Rhodes R.G.,
RA Goltsman E., Wang W., Xu J., Hunnicutt D.W., Staroscik A.M., Hoover T.R.,
RA Cheng Y.Q., Stein J.L.;
RT "Novel features of the polysaccharide-digesting gliding bacterium
RT Flavobacterium johnsoniae as revealed by genome sequence analysis.";
RL Appl. Environ. Microbiol. 75:6864-6875(2009).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP000685; ABQ05120.1; -; Genomic_DNA.
DR RefSeq; WP_012024160.1; NZ_MUGZ01000007.1.
DR STRING; 376686.Fjoh_2090; -.
DR KEGG; fjo:Fjoh_2090; -.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_000022_2_2_10; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000006694; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd19531; LCL_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020459; AMP-binding.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR PRINTS; PR00154; AMPBINDING.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1019..1094
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1568 AA; 181589 MW; E064803DF63CE6DD CRC64;
MEIRLLIKRL REEGVIVKMK NDQLEISLLY NHIEDETLQL LKTHKLEIID YLSTILSKNK
IVEIPLVKKA DSYPLTASQN RFWIVSQFED ASLAYNMPIA LKLKGQLDVV KFEQSFLHLL
ERHESLRTSF KINEEGDLRQ FITSMHDLDF SLNYIDLSLN AETEKAVEEY ITNQKEIVFN
LEKAPLVRVS LIKSAENEYV FFMTMHHIIG DGWSSELLVK EVITIYNCLI ESKEISLPEL
KIQYKDYASW LNEESQQQLY KKAETYWLNQ FSGSLPVVEL PSSKKRPLMK TYNGDFVNHQ
FTVTFLEKLT AFSHKHDVTL FMTLMAGINA LLSRYTGQQD IIIGSPIAGR EHPDLENQIG
LYLNTLAFRT KIDKGFNFID LLRHEKDVIL GSYEHQNYPF DELVDKLELK RDNSRSVLFD
VMVILQSQSK LNNFESGKLE NLEFKEYKLN TKTSKFDFAF SFTEKTDSLS LEINYNTDIY
DAFFVEKIAS HFEQLITEMI DQPETKILDI DYLSKKEKQL ILTDFNNTAA YYTEDKSIVQ
LFEQQAAKTP DHTAVIFEDK KVSYQALNEQ ANQLGGYLRK HYNIQPDDLI GIKLQRNERM
ITAILGILKS GAAYVPIDLS YPQSRIEYIE KDSNCRIIID ESFLQSFYEE QHKYSVVNIE
NRNTPKDLAY IIYTSGTTGN PKGVMVEHKN AIALVNWSKE EYAKSAFDMV YGVTSYCFDL
SVYEFFFTLA IGKTLRILKN ALDIENYINT DQNVLLNTVP SVVRKLLEDK ISLENIKVIN
MAGEILPTDI VDQLPIEKME VRNLYGPSED TTYSTSHLVI SKTNRTISIG RPMSNTQAWI
LNESLLPVPV GISGKLYLSG EGVTRGYLNK PELTAEKFVT NPFIENERMY DTGDLAYWLP
DGNIEFLGRK DHQVKIRGFR IELGEIEAAL LQYSTDLKQV VAAVKEVNGE KILAAYYIST
KELDKSSLRA FLKDKLPEYM VPGFYVRLES LPLTPNGKID REILPGINGE DLIRKEYEAP
KNDIEKKLAE IWQEILSLKE VGIHDNFFEL GGHSMKAMKL ISKIKQEFNI NFKISEIFIH
PTLLSQAEQI VSQEKNFNDT IPLLKKETSY PVSFAQRRLL PLSQIKESSV AYNMPMKLVI
NGYDPDLFIE ALHAVVERHE ILRTVFQEDA NGNFRQFVKT NEELGLKIKT YDFTKNQNPY
KEVFDYVSKD SLEPFDIKRG PLVRFALLKT AENTFVFYSN FHHIIFDGWS YKVLKKDIEV
FYNAFKNLEK PLLPDLRIQY KDFTAWQLKT IEGDEYKNQK NFWLNQFLGE IPQLNLSFAD
KRPNFKTYNG SMLTYLIKEE NFESFVKLTN TTGSTPFLNL LGIAAMVLYK NSLQKEIIIG
SPVSGRVHPD LDDQVGFYVN TLPLRIFLEE DKTYQDFIET IKETVLSCFD NQSYPFDILT
EDLNQGRDLS RSPLFDVMLN LNEYEVINES SIKAGQYAEE ETASKYDLLL EFDLFKDNLQ
CRFTYNTDLF GKKDIEKLIQ EFEKLLETVS QDQQYPLINY LNLIMSQEEL LEQEDFFSAI
ISEISEEF
//
