ID A5GLZ6_SYNPW Unreviewed; 844 AA.
AC A5GLZ6;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit clpA homolog {ECO:0000313|EMBL:CAK23961.1};
GN Name=clpA {ECO:0000313|EMBL:CAK23961.1};
GN OrderedLocusNames=SynWH7803_1535 {ECO:0000313|EMBL:CAK23961.1};
OS Synechococcus sp. (strain WH7803).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=32051 {ECO:0000313|EMBL:CAK23961.1, ECO:0000313|Proteomes:UP000001566};
RN [1] {ECO:0000313|Proteomes:UP000001566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH7803 {ECO:0000313|Proteomes:UP000001566};
RG Genoscope;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; CT971583; CAK23961.1; -; Genomic_DNA.
DR AlphaFoldDB; A5GLZ6; -.
DR STRING; 32051.SynWH7803_1535; -.
DR KEGG; syx:SynWH7803_1535; -.
DR eggNOG; COG0542; Bacteria.
DR HOGENOM; CLU_005070_4_1_3; -.
DR Proteomes; UP000001566; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF155; CLP PROTEASE ATP-BINDING SUBUNIT; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:CAK23961.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:CAK23961.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001566};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}; Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 1..131
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 407..442
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 447..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 92890 MW; 31790D14F4493AD8 CRC64;
MLAQEEARRL GHNFVGTEQI LLGLIGEGTG VAAKVLKSMG VNLKDARVEV EKIIGRGSGF
VAVEIPFTPR AKRVLELSLE EARQLGHNYI GTEHLLLGLI REGEGVAARV LENLGVDLSK
VRTQVIRMLG ETAEVGAGGS GSGSKGSTKT PTLDEFGNNL TQLAGEAKLD PVVGRQSEID
RVIQILGRRT KNNPVLIGEP GVGKTAIAEG LAQRIQQGDI PDILEDKRVL TLDIGLLVAG
TKYRGEFEER LKKIMEEIKA AGNVILVIDE VHTLIGAGAA EGAIDAANIL KPALARGELQ
CIGATTLDEY RKHIERDAAL ERRFQPVTVG EPSIDDTIEI LKGLRERYEQ HHRLRITDEA
LEAAATLGDR YISDRFLPDK AIDLIDEAGS RVRLMNSKLP PEAKEVDKEL RAVQKEKEDA
VREQDFSRAG ELRDKEVELR DKIRSLLQSS REDSPSDNQQ SEDQATDVDV ASTESEGATE
LAVTGTTPVV NEEDIAQIVA SWTGVPVQKL TESESVKLLN MEETLHKRLI GQDEAVKAVS
KAIRRARVGL KNPNRPIASF IFSGPTGVGK TELTKALAAY FFGSEEAMIR LDMSEFMERH
TVSKLIGSPP GYVGFNEGGQ LTEAVRRRPY TVVLFDEIEK AHPDVFNLLL QLLEDGRLTD
SKGRTVDFKN TLIIMTSNIG SKVIEKGGGG LGFEFSGENA EENQYNRIRS LVNEELKQYF
RPEFLNRLDE IIVFRQLNRD EVKEIAEIML REVFGRIGEK GITLTVSDAF KERLVEEGYN
PAYGARPLRR AVMRLLEDSL AEEVLSGRIK DGDEAEVDVE DGKVVVKHLN RTATETPELA
SAGR
//
