ID A5GR49_SYNR3 Unreviewed; 444 AA.
AC A5GR49;
DT 12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 12-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN OrderedLocusNames=SynRCC307_0455 {ECO:0000313|EMBL:CAK27358.1};
OS Synechococcus sp. (strain RCC307).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=316278 {ECO:0000313|EMBL:CAK27358.1, ECO:0000313|Proteomes:UP000001115};
RN [1] {ECO:0000313|EMBL:CAK27358.1, ECO:0000313|Proteomes:UP000001115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC307 {ECO:0000313|Proteomes:UP000001115};
RA Genoscope;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CT978603; CAK27358.1; -; Genomic_DNA.
DR AlphaFoldDB; A5GR49; -.
DR STRING; 316278.SynRCC307_0455; -.
DR KEGG; syr:SynRCC307_0455; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_3_1_3; -.
DR OrthoDB; 9762913at2; -.
DR Proteomes; UP000001115; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07087; ALDH_F3-13-14_CALDH-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000001115}.
FT DOMAIN 13..416
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 199
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 233
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 444 AA; 48639 MW; 47818ED30B53B63D CRC64;
MQQLVRVGST RQLAWRQQQL NNLEALLQEL ETPLRAALAT DLGKPAVEAF FEIVGVQGEL
KLAKKQLKRW MAPRRVTLPA VQQPGRTWVQ DEPLGTVLIL GPWNYPLMLV LRPLVSALAA
GNTAVLKPSE QAPALAQLLA EMVPRHFEAD VVRVELGGAE TAQALLKQPF DHVVFTGGTT
IGREVMKAAA EQLIPVTLEL GGKSPCIVLD DADLQVSARR IAWGRFLNAG QSCVAPDYVL
VTPAMRQPFE AALKEAIAEF YGPDPRQSPD FGRLVSTRQF DRVDALLKDA TVLHGGERVR
EERYIAPTLV EGDPNSALMQ EEIFAPVLPL IEVSDLEAAL RFIAERPKPL AAYLFSRSNT
ARQQLIERSQ SGSVAFNDVI VQAGVPGLPF GGVGPSGIGR CHGEAGFRSL SNQKSVYQRP
FALDLAWRYP PYGNRLSLLK RLLG
//
