ID A5I2D4_CLOBH Unreviewed; 668 AA.
AC A5I2D4; A7G431;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:CAL83201.1};
GN OrderedLocusNames=CBO1666 {ECO:0000313|EMBL:CAL83201.1};
OS Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=441771 {ECO:0000313|EMBL:CAL83201.1, ECO:0000313|Proteomes:UP000001986};
RN [1] {ECO:0000313|EMBL:CAL83201.1, ECO:0000313|Proteomes:UP000001986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger]
RC {ECO:0000313|Proteomes:UP000001986};
RX PubMed=17519437; DOI=10.1101/gr.6282807;
RA Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA White B., Whithead S., Parkhill J.;
RT "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT Hall A and comparative analysis of the clostridial genomes.";
RL Genome Res. 17:1082-1092(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM412317; CAL83201.1; -; Genomic_DNA.
DR RefSeq; WP_011986301.1; NC_009698.1.
DR RefSeq; YP_001254164.1; NC_009495.1.
DR RefSeq; YP_001387546.1; NC_009698.1.
DR AlphaFoldDB; A5I2D4; -.
DR GeneID; 5185921; -.
DR KEGG; cbh:CLC_1690; -.
DR KEGG; cbo:CBO1666; -.
DR PATRIC; fig|413999.7.peg.1638; -.
DR HOGENOM; CLU_000445_107_19_9; -.
DR Proteomes; UP000001986; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001986};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 283..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 382..632
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 668 AA; 74905 MW; 80C74C687932B9A4 CRC64;
MRSIKSKIIA IISIVCILSI GLCSSISYYF SYKAIMKETT NKVSMASQKY SEIIEGWLLT
KTKFIDSMIL DIQYNDKYDK KYLEEYFRLQ AKANKDIISI YSGFNNKEFR SIEGVPPTQN
YDCTQRPWYK DTIEKNEVMY SSPYLDPNTK KMIITIAKPI KKDGKSIGVL AIDITLDYIK
NSVEQATPVE KSYGFLLDKD NNFIVHRNRE FQPKDGKNYN VKEVMDKGLE KLASLDSKNN
NALILKDFDN EKKVFTKTII PSSKWSIGFV VPLSEFKKPL NNIIISFISI AILCLVAGTL
FAIYSAKRIS DPILKITELV NETKSLNLKD DYNYDYINSY KDEVGIIGKA VIHLREELRN
IIEELKNSSN DVLKYSESIN EATGETVQSI DAISKTVDEL AQGSVDQAKD AQNGSERLFT
LAEEIKITDE SADLVKKYSL ETKENSEKGI ATMKETIEKF KENNKVNKEL GNNVDMLANR
SGSIGEIINS IQSIAQQTNL LALNAAIEAA RAGEVGKGFA VVAEEIRKLA EQTSTSTKEI
ENIVEEIQFE INKTKDNMDV SQRVVQEVNG AMNISKESFD NITNSIEIIV EQIELLVHNV
KKVDSDKDEV LASVQGISAI AEESAASTEE VSATVEQQAA SMESMSQTAE NLKEIASTLD
TVVNKFEI
//
