ID A5I301_CLOBH Unreviewed; 567 AA.
AC A5I301; A7G4G1;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=DNA repair protein RecN {ECO:0000256|ARBA:ARBA00021315, ECO:0000256|PIRNR:PIRNR003128};
DE AltName: Full=Recombination protein N {ECO:0000256|ARBA:ARBA00033408, ECO:0000256|PIRNR:PIRNR003128};
GN Name=recN {ECO:0000313|EMBL:CAL83418.1};
GN Synonyms=radB {ECO:0000313|EMBL:CAL83418.1};
GN OrderedLocusNames=CBO1877 {ECO:0000313|EMBL:CAL83418.1};
OS Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=441771 {ECO:0000313|EMBL:CAL83418.1, ECO:0000313|Proteomes:UP000001986};
RN [1] {ECO:0000313|EMBL:CAL83418.1, ECO:0000313|Proteomes:UP000001986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger]
RC {ECO:0000313|Proteomes:UP000001986};
RX PubMed=17519437; DOI=10.1101/gr.6282807;
RA Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA White B., Whithead S., Parkhill J.;
RT "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT Hall A and comparative analysis of the clostridial genomes.";
RL Genome Res. 17:1082-1092(2007).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000256|PIRNR:PIRNR003128}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000256|ARBA:ARBA00009441,
CC ECO:0000256|PIRNR:PIRNR003128}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM412317; CAL83418.1; -; Genomic_DNA.
DR RefSeq; WP_011986438.1; NC_009698.1.
DR RefSeq; YP_001254379.1; NC_009495.1.
DR RefSeq; YP_001387676.1; NC_009698.1.
DR AlphaFoldDB; A5I301; -.
DR GeneID; 5186132; -.
DR KEGG; cbh:CLC_1821; -.
DR KEGG; cbo:CBO1877; -.
DR PATRIC; fig|413999.7.peg.1849; -.
DR HOGENOM; CLU_018297_3_1_9; -.
DR Proteomes; UP000001986; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR CDD; cd03241; ABC_RecN; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR NCBIfam; TIGR00634; recN; 1.
DR PANTHER; PTHR11059; DNA REPAIR PROTEIN RECN; 1.
DR PANTHER; PTHR11059:SF0; DNA REPAIR PROTEIN RECN; 1.
DR Pfam; PF13476; AAA_23; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|PIRNR:PIRNR003128};
KW DNA repair {ECO:0000256|PIRNR:PIRNR003128};
KW Reference proteome {ECO:0000313|Proteomes:UP000001986}.
FT DOMAIN 4..215
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 332..366
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 567 AA; 64832 MW; 70F0FE4FAC43B7B2 CRC64;
MLLQLNIKNF ALIEELSISF DKGFNVLTGE TGAGKSILID AISYVLGGKF NRDLIRTGEN
KTYVEAIFSI ENESTERILK DQGIDFEDIL IIGRETFQYG KSIAKVNAKS VLLANLKEIT
STLLDIHGQH ENQNLLSCEN HINYLDYFSE KELYSIMEKY KSEYLNLLNI ENKIKELSGG
DESEREKLMD FLKYQIKEIG ESNLKEGEEE ELDNKFLELS NAEKISKVLN NSYGILYGGL
EEESSAFDSL GYVIREMESI NSIDKITSIC QSLKDAYYII EESIRNIGDI KDNIYYDENE
LDRINSRLFQ ISTLKKKYGT TIKEIIEYKD KIEKQYEDMI NSEEIIEKLN NDRKKVLNNL
KEIAMQMHNV RVKYAEELEV RVKEELSYVG LSKTRFKINV DLVSSFFKSG CDKVEFYVST
NPGEPLKPLD KVVSGGELSR IMLALKTVFV DKDKIPSVIF DEIDTGISGV VAQSVGEKMY
SISHGRQVFC ITHLSQIACM SDNHYYIHKE VLQDKTYTKV TKLSKEDKEI EIGKMIGGSN
LTDITLQNAK EIIKIADNKK EKILKNS
//
