ID A5I3S1_CLOBH Unreviewed; 697 AA.
AC A5I3S1; A7G575;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=Regulatory protein {ECO:0000313|EMBL:CAL83690.1};
GN OrderedLocusNames=CBO2149 {ECO:0000313|EMBL:CAL83690.1};
OS Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=441771 {ECO:0000313|EMBL:CAL83690.1, ECO:0000313|Proteomes:UP000001986};
RN [1] {ECO:0000313|EMBL:CAL83690.1, ECO:0000313|Proteomes:UP000001986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger]
RC {ECO:0000313|Proteomes:UP000001986};
RX PubMed=17519437; DOI=10.1101/gr.6282807;
RA Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA White B., Whithead S., Parkhill J.;
RT "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT Hall A and comparative analysis of the clostridial genomes.";
RL Genome Res. 17:1082-1092(2007).
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DR EMBL; AM412317; CAL83690.1; -; Genomic_DNA.
DR RefSeq; WP_011986653.1; NC_009698.1.
DR RefSeq; YP_001254646.1; NC_009495.1.
DR RefSeq; YP_001387940.1; NC_009698.1.
DR AlphaFoldDB; A5I3S1; -.
DR GeneID; 5186404; -.
DR KEGG; cbh:CLC_2093; -.
DR KEGG; cbo:CBO2149; -.
DR PATRIC; fig|413999.7.peg.2119; -.
DR HOGENOM; CLU_013442_1_1_9; -.
DR Proteomes; UP000001986; Chromosome.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR CDD; cd05568; PTS_IIB_bgl_like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR PANTHER; PTHR30185:SF18; TRANSCRIPTIONAL REGULATOR MTLR; 1.
DR Pfam; PF08279; HTH_11; 2.
DR Pfam; PF00874; PRD; 2.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51372; PRD_2; 2.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS00372; PTS_EIIA_TYPE_2_HIS; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001986};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 185..290
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 294..401
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 406..496
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
FT DOMAIN 555..697
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 697 AA; 80182 MW; CD7CD2DFE3F588FC CRC64;
MLNKRCSNIL QMIVNNEKPI TIKEISKKVN KSPRTVRYDL DKIDDYLTEI EFPKLERKSN
LGISLDLKDE EIKKLFKIIG KINNYDYVLS QKERVFYIIY ELLNKSEFVT INMLSDRMMV
SRSTIINDLI EVKKWLSENK ITLESSKGQG IKILGRERDL RRAAVKLFFQ SMDSINFFNV
TTLKLFNDID IDFIRNTIKI AEEQMETSFS DDAFNNLVIH IAIAIKRIEL SKDIIMDSEE
LKNLRKTAEY AIASGIAKML EDRFKISIPE DEIGYITIHI LGSNTSTLEN IVKDDWIYLH
LIVFKLIENV ENITGINFSK DNKLFDSLAQ HIRPAIYRLK HDIKVKNPLI EEIKEKYSYI
FESIEEGVKF IEEDIGDSVN QEEIGYLTLH FMASIERSKN KKHRKPNVLI VCATGIGTSK
FISNKLKSIF DINIIDTISS HTMEKILKYN KNIDLIVTTI PLKVKGIKCI EVNTFLTEKN
ISELGLYFAK FIRNNSEECN GSCKYEERDK VQEILNIVKE NCTIHDYYKL RNKLALYLNI
KDPTLTEDHK PSLKELLKPD FIKLNEEAEN WEDAVRKSGE ILMNNGCVKE SYIDAMVNTV
KNMGPYIVIA PGIAMPHAAP EDGVLKTGIS MLTLKDPISF GNSEHDPVSV IISICSIDKV
NHMKALKELM SIMDQEDFIS KVKNIKASSE IDSILYS
//
